| Literature DB >> 27771445 |
Paul A Ellison1, Hector F Valdovinos1, Stephen A Graves1, Todd E Barnhart1, Robert J Nickles2.
Abstract
Zirconium-89 finds broad application for use in positron emission tomography. Its cyclotron production has been limited by the heat transfer from yttrium targets at high beam currents. A spot welding technique allows a three-fold increase in beam current, without affecting 89Zr quality. An yttrium foil, welded to a jet-cooled tantalum support base accommodates a 50µA proton beam degraded to 14MeV. The resulting activity yield of 48±4 MBq/(μA∙hr) now extends the outreach of 89Zr for a broader distribution.Entities:
Keywords: (89)Zr; Cyclotron solid targetry; Spot welding; Ti-44; Zirconium-89; Zr-89
Year: 2016 PMID: 27771445 PMCID: PMC5164840 DOI: 10.1016/j.apradiso.2016.10.010
Source DB: PubMed Journal: Appl Radiat Isot ISSN: 0969-8043 Impact factor: 1.513