Ricarda Lechner1, David Putzer2, Michael Liebensteiner1, Christian Bach3, Martin Thaler4. 1. Department of Orthopaedic Surgery, Medical University Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria. 2. Department of Orthopaedic Surgery-Experimental Orthopaedics, Medical University Innsbruck, Innrain 36, 6020, Innsbruck, Austria. 3. Department of Orthopaedic Surgery, Landeskrankenhaus Feldkirch, Carinagasse 47, 6807, Feldkirch, Austria. 4. Department of Orthopaedic Surgery, Medical University Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria. martin.thaler@i-med.ac.at.
Abstract
PURPOSE: Bone graft substitutes have been successfully used in posterolateral lumbar fusion, anterior cervical fusion and animal studies. This study has been conducted to assess the safety and efficacy of β-tricalcium phosphate (β-TCP) in instrumented anterior lumbar interbody fusion (ALIF) procedure. METHODS: In a prospective clinical study, ALIF cages were prefilled with β-TCP and additionally fixated with posterior pedicle screw. Computed tomography (CT) and X-rays were performed one year after surgery. Fusion was assessed and functional status was evaluated before and one year after surgery. RESULTS: X-ray evaluation showed a definite fusion in 85.48 % of treated levels. CT assessment showed anterior and posterior intersegemental bone bridging in 77.78 % of treated levels. CONCLUSIONS: The X-ray fusion rate presented is comparable with those published for ALIF procedures with bone graft. Fusion rates β-TCP are similar to autologous bone. ALIF with β-TCP and additional posterior fixation is a safe and effective procedure.
PURPOSE: Bone graft substitutes have been successfully used in posterolateral lumbar fusion, anterior cervical fusion and animal studies. This study has been conducted to assess the safety and efficacy of β-tricalcium phosphate (β-TCP) in instrumented anterior lumbar interbody fusion (ALIF) procedure. METHODS: In a prospective clinical study, ALIF cages were prefilled with β-TCP and additionally fixated with posterior pedicle screw. Computed tomography (CT) and X-rays were performed one year after surgery. Fusion was assessed and functional status was evaluated before and one year after surgery. RESULTS: X-ray evaluation showed a definite fusion in 85.48 % of treated levels. CT assessment showed anterior and posterior intersegemental bone bridging in 77.78 % of treated levels. CONCLUSIONS: The X-ray fusion rate presented is comparable with those published for ALIF procedures with bone graft. Fusion rates β-TCP are similar to autologous bone. ALIF with β-TCP and additional posterior fixation is a safe and effective procedure.
Entities:
Keywords:
Anterior lumbar interbody fusion; Bone graft substitute; Bone marrow aspirate; Calcium phosphate; Donor site complication
Authors: Andreas H Kröner; Richard Eyb; Andreas Lange; Kristina Lomoschitz; Taher Mahdi; Alfred Engel Journal: Spine (Phila Pa 1976) Date: 2006-05-20 Impact factor: 3.468
Authors: A O Ransford; T Morley; M A Edgar; P Webb; N Passuti; D Chopin; C Morin; F Michel; C Garin; D Pries Journal: J Bone Joint Surg Br Date: 1998-01