Literature DB >> 27761030

Routine Treatment of Cervical Cytological Cell Changes: Diagnostic Standard, Prevention and Routine Treatment of Cervical Cytological Cell Changes - An Assessment of Primary and Secondary Prevention and Routine Treatment Data in the Context of an Anonymous Data Collection from Practicing Gynaecologists; an Academic, Non-Interventional Study.

J Huber1, B Pötsch2, M Gantschacher3, M Templ4.   

Abstract

Introduction: Diagnosis and treatment of vaginal and cervical cytological cell changes are described in European and national guidelines. The aim of this data collection was to evaluate the remission rates of PAP III and PAP III D cytological findings in patients over a period of 3-4 months. Method: The current state of affairs in managing suspicious and cytological findings (PAP III, and III D) in gynecological practice was assessed in the context of a data collection survey. An evaluation over a period of 24 months was conducted on preventative measures, the occurrence and changes to normal/suspect/pathological findings and therapy management (for suspicious or pathological findings).
Results: 307 female patients were included in the analysis. At the time of the survey 186 patients (60.6 %) had PAP III and 119 (38.8 %) had PAP III D findings. The spontaneous remission rate of untreated PAP III patients was 6 % and that of untreated PAP III D patients was 11 %. The remission rates of patients treated with a vaginal gel were 77 % for PAP III and 71 % for PAP III D.
Conclusion: A new treatment option was used in gynecological practice on patients with PAP III and PAP III D findings between confirmation and the next follow-up with excellent success.

Entities:  

Keywords:  PAP III; PAP III D; cervix; gynaecology

Year:  2016        PMID: 27761030      PMCID: PMC5065416          DOI: 10.1055/s-0042-105286

Source DB:  PubMed          Journal:  Geburtshilfe Frauenheilkd        ISSN: 0016-5751            Impact factor:   2.915


  22 in total

1.  Empiric vaginal metronidazole in the management of the ASCUS Papanicolaou smear: a randomized controlled trial.

Authors:  Joseph P Connor; Gloria Elam; Jeffrey M Goldberg
Journal:  Obstet Gynecol       Date:  2002-02       Impact factor: 7.661

Review 2.  [Epidemiology and diagnosis of cervical intraepithelial neoplasia--is the present concept of screening and diagnosis still current?].

Authors:  P Hillemanns; C Thaler; R Kimmig
Journal:  Gynakol Geburtshilfliche Rundsch       Date:  1997

3.  The mildly abnormal cervical smear: patient anxiety and choice of management.

Authors:  M H Jones; A Singer; D Jenkins
Journal:  J R Soc Med       Date:  1996-05       Impact factor: 5.344

Review 4.  More than a decade on: review of the use of imiquimod in lower anogenital intraepithelial neoplasia.

Authors:  M Mahto; M Nathan; C O'Mahony
Journal:  Int J STD AIDS       Date:  2010-01       Impact factor: 1.359

5.  Recombinant human interferon gamma in the treatment of cervical intraepithelial neoplasia (CIN) associated with human papillomavirus (HPV) infection.

Authors:  M Sikorski; H Zrubek
Journal:  Eur J Gynaecol Oncol       Date:  2003       Impact factor: 0.196

6.  No effect of intralesional injection of interferon on moderate cervical intraepithelial neoplasia.

Authors:  L Frost; K Skajaa; L E Hvidman; S J Fay; P M Larsen
Journal:  Br J Obstet Gynaecol       Date:  1990-07

7.  Women's experience of coping with a positive Pap smear: A register-based study of women with two consecutive Pap smears reported as CIN 1.

Authors:  Monica Ideström; Ian Milsom; Agneta Andersson-Ellström
Journal:  Acta Obstet Gynecol Scand       Date:  2003-08       Impact factor: 3.636

Review 8.  The 2001 Bethesda System terminology.

Authors:  Barbara S Apgar; Lauren Zoschnick; Thomas C Wright
Journal:  Am Fam Physician       Date:  2003-11-15       Impact factor: 3.292

9.  A randomized, double-blind, placebo-controlled trial of 5-fluorouracil for the treatment of cervicovaginal human papillomavirus.

Authors:  M M Holmes; S H Weaver; S T Vermillion
Journal:  Infect Dis Obstet Gynecol       Date:  1999

10.  Psychological effects of a low-grade abnormal cervical smear test result: anxiety and associated factors.

Authors:  N M Gray; L Sharp; S C Cotton; L F Masson; J Little; L G Walker; M Avis; Z Philips; I Russell; D Whynes; M Cruickshank; C M Woolley
Journal:  Br J Cancer       Date:  2006-05-08       Impact factor: 7.640

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  1 in total

Review 1.  Human papillomavirus persistence or clearance after infection in reproductive age. What is the status? Review of the literature and new data of a vaginal gel containing silicate dioxide, citric acid, and selenite.

Authors:  Johannes Huber; Anna Mueller; Manuela Sailer; Pedro-Antonio Regidor
Journal:  Womens Health (Lond)       Date:  2021 Jan-Dec
  1 in total

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