| Literature DB >> 27750120 |
Tjerk J Sminia1, Han Zuilhof1, Tom Wennekes2.
Abstract
This review discusses the advances in metabolic oligosaccharide engineering (MOE) from 2010 to 2016 with a focus on the structure, preparation, and reactivity of its chemical probes. A brief historical overview of MOE is followed by a comprehensive overview of the chemical probes currently available in the MOE molecular toolbox and the bioconjugation techniques they enable. The final part of the review focusses on the synthesis of a selection of probes and finishes with an outlook on recent and potential upcoming advances in the field of MOE.Entities:
Keywords: Bio-orthogonal reactions; Chemical probes; Glycans; Glycobiology; Metabolic oligosaccharide engineering
Mesh:
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Year: 2016 PMID: 27750120 DOI: 10.1016/j.carres.2016.09.007
Source DB: PubMed Journal: Carbohydr Res ISSN: 0008-6215 Impact factor: 2.104