Literature DB >> 27738787

Integrated non-invasive approach to atherosclerosis with cardiac CT and carotid ultrasound in patients with suspected coronary artery disease.

Ludovico La Grutta1, Marta Marasà2, Patrizia Toia2, Daniele Ajello2, Domenico Albano2, Erica Maffei3, Emanuele Grassedonio2, Giuseppina Novo4, Massimo Galia2, Giuseppe Caruso2, Salvatore Novo4, Filippo Cademartiri3,5, Massimo Midiri2.   

Abstract

OBJECTIVE: The aim of the study was to compare the atherosclerotic disease in the coronary and carotid arteries in patients who underwent non-invasive imaging for suspected stable coronary artery disease (CAD).
MATERIALS AND METHODS: 107 patients (64 men, age 59 ± 12) with atypical chest pain underwent cardiac CT (CCT) and carotid ultrasound (US) on the same day. Severity (obstructive or not-obstructive disease), location, shape, and composition of atherosclerotic plaques in the two districts were evaluated.
RESULTS: Patients presented normal coronary arteries in 36 % (n = 38), not-obstructive CAD in 36 % (n = 39), and obstructive CAD in 28 % (n = 30), while had normal carotid arteries in 53 % (n = 57), not-obstructive disease in 44 % (n = 47), and obstructive disease in 3 % (n = 3) (p < 0.05). The coronary plaques were located in 7 % at ostial sites, in 29 % at non-ostial sites, and in 64 % at both locations. The carotid plaques were located at the origin of the internal and external carotid arteries in 56 %, at the bifurcation in 20 %, and at both locations in 24 % (p < 0.05). Coronary plaques were calcified in 25 %, non-calcified in 19 %, and mixed in 56 %; carotid plaques were calcified in 8 %, non-calcified in 8 %, and mixed in 84 % of patients (p < 0.05).
CONCLUSION: Atherosclerotic disease presents different imaging findings in the coronary tree and in the carotid district with respect to lesion severity, position along the vessel course, and composition of plaque.

Entities:  

Keywords:  Atherosclerosis; Cardiac CT; Carotid arteries; Coronary artery disease; Doppler ultrasound

Mesh:

Substances:

Year:  2016        PMID: 27738787     DOI: 10.1007/s11547-016-0692-8

Source DB:  PubMed          Journal:  Radiol Med        ISSN: 0033-8362            Impact factor:   3.469


  33 in total

Review 1.  Imaging techniques for the vulnerable coronary plaque.

Authors:  F Cademartiri; L La Grutta; A Palumbo; E Maffei; A Aldrovandi; R Malagò; F Alberghina; F Pugliese; G Runza; M Belgrano; M Midiri; M A Cova; G P Krestin
Journal:  Radiol Med       Date:  2007-07-24       Impact factor: 3.469

2.  Comparison of 128-Slice Dual Source CT Coronary Angiography with Invasive Coronary Angiography.

Authors:  Rajneesh Madhok; Abhinav Aggarwal
Journal:  J Clin Diagn Res       Date:  2014-06-20

3.  320-row coronary computed tomography angiography (CCTA) with automatic exposure control (AEC): effect of 100 kV versus 120 kV on image quality and dose exposure.

Authors:  Ernesto Di Cesare; Antonio Gennarelli; Alessandra Di Sibio; Valentina Felli; Marco Perri; Alessandra Splendiani; Giovanni Luca Gravina; Antonio Barile; Carlo Masciocchi
Journal:  Radiol Med       Date:  2016-05-12       Impact factor: 3.469

4.  Associations of extracranial carotid atherosclerosis progression with coronary status and risk factors in patients with and without coronary artery disease.

Authors:  John R Crouse; Rong Tang; Mark A Espeland; James G Terry; Timothy Morgan; Michele Mercuri
Journal:  Circulation       Date:  2002-10-15       Impact factor: 29.690

5.  A negative carotid plaque area test is superior to other noninvasive atherosclerosis studies for reducing the likelihood of having underlying significant coronary artery disease.

Authors:  Robert D Brook; Robert L Bard; Smita Patel; Melvyn Rubenfire; Nicholas S Clarke; Ella A Kazerooni; Thomas W Wakefield; Peter K Henke; Kim A Eagle
Journal:  Arterioscler Thromb Vasc Biol       Date:  2005-12-15       Impact factor: 8.311

6.  Usefulness of carotid intima-media thickness measurement as an indicator of generalized atherosclerosis: findings from autopsy analysis.

Authors:  Takashi Iwakiri; Yuichiro Yano; Yuichiro Sato; Kinta Hatakeyama; Kousuke Marutsuka; Shouichi Fujimoto; Kazuo Kitamura; Kazuomi Kario; Yujiro Asada
Journal:  Atherosclerosis       Date:  2012-10-12       Impact factor: 5.162

Review 7.  Value and limitations of existing scores for the assessment of cardiovascular risk: a review for clinicians.

Authors:  Marie Therese Cooney; Alexandra L Dudina; Ian M Graham
Journal:  J Am Coll Cardiol       Date:  2009-09-29       Impact factor: 24.094

8.  Role of Cardiac Computed Tomography in the Evaluation of Coronary Artery Stenosis in Patients With Ascending Aorta Aneurysm Detected at Transthoracic Echocardiography.

Authors:  Ludovico La Grutta; Patrizia Toia; Massimo Galia; Emanuele Grassedonio; Daniele Ajello; Giuseppina Novo; Tommaso Vincenzo Bartolotta; Erica Maffei; Salvatore Novo; Filippo Cademartiri; Roberto Lagalla; Massimo Midiri
Journal:  J Comput Assist Tomogr       Date:  2016 May-Jun       Impact factor: 1.826

Review 9.  Carotid plaque compared with intima-media thickness as a predictor of coronary and cerebrovascular disease.

Authors:  Stein Harald Johnsen; Ellisiv B Mathiesen
Journal:  Curr Cardiol Rep       Date:  2009-01       Impact factor: 2.931

10.  Early atherosclerosis detection in asymptomatic patients: a comparison of carotid ultrasound, coronary artery calcium score, and coronary computed tomography angiography.

Authors:  Benjamin Schroeder; Gordon Francis; Jonathon Leipsic; Brett Heilbron; G B John Mancini; Carolyn M Taylor
Journal:  Can J Cardiol       Date:  2013-10-05       Impact factor: 5.223

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  4 in total

1.  Coronary CT Angiography and Carotid MRI Improve Phenotyping of Disease Extent Compared with ACC/AHA Risk Score Alone.

Authors:  Ashley Chorath; Younhee Choi; Evrim B Turkbey; Mark A Ahlman; Christopher T Sibley; Songtao Liu; David A Bluemke; Veit Sandfort
Journal:  Radiol Cardiothorac Imaging       Date:  2020-02-27

Review 2.  Old and New NICE Guidelines for the Evaluation of New Onset Stable Chest Pain: A Real World Perspective.

Authors:  Nazario Carrabba; Angela Migliorini; Silvia Pradella; Manlio Acquafresca; Marco Guglielmo; Andrea Baggiano; Giuseppe Moscogiuri; Renato Valenti
Journal:  Biomed Res Int       Date:  2018-11-08       Impact factor: 3.411

Review 3.  Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review.

Authors:  Patrizia Carità; Andrea Igoren Guaricci; Giuseppe Muscogiuri; Nazario Carrabba; Gianluca Pontone
Journal:  Biomed Res Int       Date:  2018-09-16       Impact factor: 3.411

4.  Comparison of carotid artery ultrasound and Framingham risk score for discriminating coronary artery disease in patients with psoriatic arthritis.

Authors:  Isaac T Cheng; Ka Tak Wong; Edmund K Li; Priscilla C H Wong; Billy T Lai; Isaac C Yim; Shirley K Ying; Kitty Y Kwok; Martin Li; Tena K Li; Jack J Lee; Alex P Lee; Lai-Shan Tam
Journal:  RMD Open       Date:  2020-09
  4 in total

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