Literature DB >> 27724053

Judging the value of 'liver-on-a-chip' devices for prediction of toxicity.

Viktoriia Starokozhko1, Geny M M Groothuis1.   

Abstract

Entities:  

Keywords:  ADME; co-cultures; drug development; drug toxicity testing; drug-induced liver injury; liver-on-a-chip; microfluidics

Mesh：

Year:  2016        PMID： 27724053     DOI： 10.1080/17425255.2017.1246537

Source DB:  PubMed          Journal:  Expert Opin Drug Metab Toxicol        ISSN： 1742-5255            Impact factor:   4.481


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  7 in total

1.  Microfluidic Disc-on-a-Chip Device for Mouse Intervertebral Disc-Pitching a Next-Generation Research Platform To Study Disc Degeneration.

Authors:  Jun Dai; Yuan Xing; Li Xiao; Jingyi Li; Ruofan Cao; Yi He; Huang Fang; Ammasi Periasamy; Jose Oberhozler; Li Jin; James P Landers; Yong Wang; Xudong Li
Journal:  ACS Biomater Sci Eng       Date:  2019-02-26

2.  A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX.

Authors:  Xiang Li; Subin M George; Lawrence Vernetti; Albert H Gough; D Lansing Taylor
Journal:  Lab Chip       Date:  2018-08-21       Impact factor: 6.799

3.  In silico approaches in organ toxicity hazard assessment: current status and future needs in predicting liver toxicity.

Authors:  Arianna Bassan; Vinicius M Alves; Alexander Amberg; Lennart T Anger; Scott Auerbach; Lisa Beilke; Andreas Bender; Mark T D Cronin; Kevin P Cross; Jui-Hua Hsieh; Nigel Greene; Raymond Kemper; Marlene T Kim; Moiz Mumtaz; Tobias Noeske; Manuela Pavan; Julia Pletz; Daniel P Russo; Yogesh Sabnis; Markus Schaefer; David T Szabo; Jean-Pierre Valentin; Joerg Wichard; Dominic Williams; David Woolley; Craig Zwickl; Glenn J Myatt
Journal:  Comput Toxicol       Date:  2021-09-09

4.  Nanoparticle-induced inflammation and fibrosis in ex vivo murine precision-cut liver slices and effects of nanoparticle exposure conditions.

Authors:  Roberta Bartucci; Alex Z van der Meer; Ykelien L Boersma; Peter Olinga; Anna Salvati
Journal:  Arch Toxicol       Date:  2021-02-08       Impact factor: 5.153

Review 5.  The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development.

Authors:  Paul A Walker; Stephanie Ryder; Andrea Lavado; Clive Dilworth; Robert J Riley
Journal:  Arch Toxicol       Date:  2020-05-06       Impact factor: 5.153

6.  Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro.

Authors:  Qiongyin Fan; Baosheng Zhao; Chunguo Wang; Jingxuan Zhang; Jinying Wu; Ting Wang; Anlong Xu
Journal:  Molecules       Date:  2018-09-28       Impact factor: 4.411

Review 7.  Microfluidic Organ-on-a-Chip Devices for Liver Disease Modeling In Vitro.

Authors:  Perizat Kanabekova; Adina Kadyrova; Gulsim Kulsharova
Journal:  Micromachines (Basel)       Date:  2022-03-10       Impact factor: 2.891
  7 in total

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