Literature DB >> 27723159

Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers.

David A Raichlen1, Herman Pontzer2,3, Jacob A Harris4, Audax Z P Mabulla5, Frank W Marlowe6, J Josh Snodgrass7, Geeta Eick7, J Colette Berbesque8, Amelia Sancilio9, Brian M Wood9.   

Abstract

OBJECTIVES: Time spent in moderate-to-vigorous physical activity (MVPA) is a strong predictor of cardiovascular health, yet few humans living in industrialized societies meet current recommendations (150 min/week). Researchers have long suggested that human physiological requirements for aerobic exercise reflect an evolutionary shift to a hunting and gathering foraging strategy, and a recent transition to more sedentary lifestyles likely represents a mismatch with our past in terms of physical activity. The goal of this study is to explore this mismatch by characterizing MVPA and cardiovascular health in the Hadza, a modern hunting and gathering population living in Northern Tanzania.
METHODS: We measured MVPA using continuous heart rate monitoring in 46 participants recruited from two Hadza camps. As part of a larger survey of health in the Hadza, we measured blood pressure (n = 198) and biomarkers of cardiovascular health (n = 23) including C-reactive protein, cholesterol (Total, HDL, and LDL), and triglycerides.
RESULTS: We show that Hadza participants spend large amounts of time in MVPA (134.92 ± 8.6 min/day), and maintain these activity levels across the lifespan. In fact, the Hadza engage in over 14 times as much MVPA as subjects participating in large epidemiological studies in the United States. We found no evidence of risk factors for cardiovascular disease in this population (low prevalence of hypertension across the lifespan, optimal levels for biomarkers of cardiovascular health).
CONCLUSIONS: Our results provide evidence that the hunting and gathering foraging strategy involves high levels of MVPA, supporting the evolutionary medicine model for the relationship between MVPA and cardiovascular health.
© 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  C-reactive protein; blood pressure; cholesterol; energetics; exercise; flex heart rate; heart-rate

Mesh:

Substances:

Year:  2016        PMID: 27723159     DOI: 10.1002/ajhb.22919

Source DB:  PubMed          Journal:  Am J Hum Biol        ISSN: 1042-0533            Impact factor:   1.937


  32 in total

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Authors:  David A Raichlen; Gene E Alexander
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2.  Coalitional Play Fighting and the Evolution of Coalitional Intergroup Aggression.

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3.  The Goldilocks Zone for Exercise: Not Too Little, Not Too Much.

Authors:  James H O'Keefe; Evan L O'Keefe; Carl J Lavie
Journal:  Mo Med       Date:  2018 Mar-Apr

4.  A new approach to estimate aerobic fitness using the NHANES dataset.

Authors:  Kim D Lu; Ronen Bar-Yoseph; Shlomit Radom-Aizik; Dan M Cooper
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Review 5.  The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans.

Authors:  Daniel E Lieberman; Timothy M Kistner; Daniel Richard; I-Min Lee; Aaron L Baggish
Journal:  Proc Natl Acad Sci U S A       Date:  2021-12-14       Impact factor: 11.205

Review 6.  Molecular aspects of fructose metabolism and metabolic disease.

Authors:  Mark A Herman; Morris J Birnbaum
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7.  Age-related decline in urine concentration may not be universal: Comparative study from the U.S. and two small-scale societies.

Authors:  Asher Y Rosinger; Herman Pontzer; David A Raichlen; Brian M Wood; Susan N Tanner; Jeff M Sands
Journal:  Am J Phys Anthropol       Date:  2019-01-31       Impact factor: 2.868

8.  Ageing and physical function in East African foragers and pastoralists.

Authors:  M Katherine Sayre; Herman Pontzer; Gene E Alexander; Brian M Wood; Ivy L Pike; Audax Z P Mabulla; David A Raichlen
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2020-09-21       Impact factor: 6.237

9.  Sitting, squatting, and the evolutionary biology of human inactivity.

Authors:  David A Raichlen; Herman Pontzer; Theodore W Zderic; Jacob A Harris; Audax Z P Mabulla; Marc T Hamilton; Brian M Wood
Journal:  Proc Natl Acad Sci U S A       Date:  2020-03-09       Impact factor: 11.205

10.  Objective and subjective measurement of sedentary behavior in human adults: A toolkit.

Authors:  Justin Aunger; Janelle Wagnild
Journal:  Am J Hum Biol       Date:  2020-12-05       Impact factor: 2.947

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