Literature DB >> 27722761

A Pilot Study of SMILE for Hyperopia: Corneal Morphology and Surface Characteristics of Concave Lenticules in Human Donor Eyes.

Jing Zhao, Huamao Miao, Tian Han, Yang Shen, Yu Zhao, Ling Sun, Xingtao Zhou.   

Abstract

PURPOSE: To evaluate the corneal morphology and surface characteristics of concave lenticules after small incision lenticule extraction (SMILE) for hyperopia.
METHODS: SMILE procedures were performed on two human autopsy corneas in vitro to correct +4.00 diopters of hyperopia. Slit-lamp microscopy and anterior optical coherence tomography (OCT) were performed after lenticule creation and extraction. The extracted lenticules and modified corneas were sent for transmission electron microscopy imaging.
RESULTS: Interlamellar gas bubbles were detected at 3 minutes and almost burst at 30 minutes after lenticule creation. A few interlamellar bubbles were detected after lenticule extraction. There was an obvious interlamellar concave gap under OCT. Transmission electron microscopy showed the front and back surfaces of the lenticules were smooth, with some tissue bridges, cavities, and grooves.
CONCLUSIONS: A good quality concave lenticule can be created via SMILE for hyperopia. The impact of interlamellar gap on visual quality needs further investigation. [J Refract Surg. 2016;32(10):713-716.]. Copyright 2016, SLACK Incorporated.

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Mesh:

Year:  2016        PMID: 27722761     DOI: 10.3928/1081597X-20160718-01

Source DB:  PubMed          Journal:  J Refract Surg        ISSN: 1081-597X            Impact factor:   3.573


  3 in total

1.  A microscopic study of the corneal stromal lenticules extracted during femtosecond laser-assisted small incision lenticule extraction.

Authors:  Yewei Yin; Tu Hu; Aiqun Xiang; Yanyan Fu; Yang Zhao; Xiaoying Wu; Xiaoying Wu; Dan Wen
Journal:  Exp Ther Med       Date:  2021-04-25       Impact factor: 2.447

2.  A pilot study: lenticule quality of hyperopic small incision lenticule extraction (SMILE) in rabbits.

Authors:  Yu Zhao; Feng Zhao; Tian Han; Jing Zhao; Xingtao Zhou
Journal:  BMC Ophthalmol       Date:  2020-04-19       Impact factor: 2.209

Review 3.  Human SMILE-Derived Stromal Lenticule Scaffold for Regenerative Therapy: Review and Perspectives.

Authors:  Mithun Santra; Yu-Chi Liu; Vishal Jhanji; Gary Hin-Fai Yam
Journal:  Int J Mol Sci       Date:  2022-07-19       Impact factor: 6.208

  3 in total

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