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Literature DB >> 27722294

Boronate based fluorescence (ESIPT) probe for peroxynitrite.

Adam C Sedgwick¹, Xiaolong Sun¹, Gyoungmi Kim², Juyoung Yoon², Steven D Bull¹, Tony D James¹.

Abstract

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting" unit. The "protecting" unit of the probe is removed by peroxynitrite to "turn-on" ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

Entities: Chemical

Year: 2016 PMID： 27722294 DOI： 10.1039/c6cc06829d

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

13 in total

1. A phenylboronate-based SERS nanoprobe for detection and imaging of intracellular peroxynitrite.

Authors: Hua-Ying Chen; Dan Guo; Zhen-Fei Gan; Lei Jiang; Shuai Chang; Da-Wei Li
Journal: Mikrochim Acta Date: 2018-12-10 Impact factor: 5.833

2. Staphylococcus aureus Lipoic Acid Synthesis Limits Macrophage Reactive Oxygen and Nitrogen Species Production To Promote Survival during Infection.

Authors: James P Grayczyk; Francis Alonzo
Journal: Infect Immun Date: 2019-09-19 Impact factor: 3.441

3. Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes.

Authors: Hai-Hao Han; Adam C Sedgwick; Ying Shang; Na Li; Tingting Liu; Bo-Han Li; Kunqian Yu; Yi Zang; James T Brewster; Maria L Odyniec; Maria Weber; Steven D Bull; Jia Li; Jonathan L Sessler; Tony D James; Xiao-Peng He; He Tian
Journal: Chem Sci Date: 2019-11-27 Impact factor: 9.825

Boronate based fluorescence (ESIPT) probe for peroxynitrite.

1. A phenylboronate-based SERS nanoprobe for detection and imaging of intracellular peroxynitrite.

2. Staphylococcus aureus Lipoic Acid Synthesis Limits Macrophage Reactive Oxygen and Nitrogen Species Production To Promote Survival during Infection.

3. Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes.

Review 4. Genetically Encoded Fluorescent Redox Indicators for Unveiling Redox Signaling and Oxidative Toxicity.

5. A Two-Photon Ratiometric Fluorescent Probe for Imaging of Hydrogen Peroxide Levels in Rat Organ Tissues.

6. Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide.

7. Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols.

8. The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH.

9. Ratiometric Polymer Probe for Detection of Peroxynitrite and the Application for Live-Cell Imaging.

10. Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species.