| Literature DB >> 27721883 |
Biagio Ricciuti1, Giulia Costanza Leonardi1, Noemi Ravaioli1, Andrea De Giglio1, Marta Brambilla1, Enrico Prosperi2, Franca Ribacchi3, Marialuisa Meacci1, Lucio Crinò1, Daniele Maiettini4, Rita Chiari1, Giulio Metro1.
Abstract
Breast cancer metastases to the gastrointestinal tract are very rare occurrences. Among the histological subtypes of breast cancer, invasive lobular carcinomas have a high capacity of metastasis to uncommon sites including the stomach. Conversely, there has not been sufficient evidence supporting the gastric metastasis of invasive ductal carcinoma. Herein, we report a unique case of metastatic ductal breast carcinoma mimicking primary linitis plastica in a male patient, particularly focusing on the clinical and pathological features of presentation. Moreover, we propose a immunohistochemical panel of selected antibodies including those for cytokeratin 20, cytokeratin 7, estrogen receptor, progesterone receptor, E-cadherin, gross cystic disease fluid protein 15, and GATA binding protein 3 for an accurate differential diagnosis.Entities:
Keywords: Biomarkers; Breast neoplasms; Human epidermal growth factor receptor 2; Linitis plastica; Neoplasm metastasis
Year: 2016 PMID: 27721883 PMCID: PMC5053318 DOI: 10.4048/jbc.2016.19.3.324
Source DB: PubMed Journal: J Breast Cancer ISSN: 1738-6756 Impact factor: 3.588