| Literature DB >> 27711344 |
Alessandra Augurusa1, Meera Mehta1, Manuel Perez1, Jiangtao Zhu1, Douglas W Stephan1.
Abstract
A catalytic methodology for the conversion of amides to amines is reported. Of the 25 examples described, 14 examples involve the reduction of N-trifluoroacetamides to the corresponding trifluoroethylamines. These reductions are achieved by catalytic hydrosilylation of the amide mediated by an electrophilic phosphonium cation (EPC) catalyst.Entities:
Year: 2016 PMID： 27711344 DOI： 10.1039/c6cc06914b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222