Metin Işık1, Hatice Şahin2, Engin Hüseyin2. 1. Department of Rheumatology, Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey. 2. Department of Internal Medicine, Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey.
Abstract
OBJECTIVE: To test new platelet indices for patients with rheumatoid arthritis (RA) as new acute phase reactants. MATERIAL AND METHODS: In total, 120 patients with RA and 40 patients in the control group were analyzed. A DAS 28 score over 2.6 was accepted as active disease, and a DAS 28 score lower than 2.6 was accepted as under remission. Platelet distribution width, plateletcrit, and mean platelet volume were analyzed for three groups: patients with active RA, patients under remission, and the control group. RESULTS: There were 72 patients with active disease and 48 patients under remission. The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), mean platelet volume (MPV), plateletcrit (PTC), and platelet distribution width (PDW) scores were all statistically different among groups. In our data, PTC was found to be a positive acute phase reactant and others were negative acute phase reactants for patients with RA. CONCLUSION: These new indices are cheap, widely available, and useful parameters for routine clinical rheumatology practice.
OBJECTIVE: To test new platelet indices for patients with rheumatoid arthritis (RA) as new acute phase reactants. MATERIAL AND METHODS: In total, 120 patients with RA and 40 patients in the control group were analyzed. A DAS 28 score over 2.6 was accepted as active disease, and a DAS 28 score lower than 2.6 was accepted as under remission. Platelet distribution width, plateletcrit, and mean platelet volume were analyzed for three groups: patients with active RA, patients under remission, and the control group. RESULTS: There were 72 patients with active disease and 48 patients under remission. The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), mean platelet volume (MPV), plateletcrit (PTC), and platelet distribution width (PDW) scores were all statistically different among groups. In our data, PTC was found to be a positive acute phase reactant and others were negative acute phase reactants for patients with RA. CONCLUSION: These new indices are cheap, widely available, and useful parameters for routine clinical rheumatology practice.
Entities:
Keywords:
Mean platelet volume; platelet distribution width; plateletcrit
Authors: C Jurcuţ; Ruxandra Jurcuţ; Simona Caraiola; Doina Niţescu; C Mihai; Anda Baicuş; I Copaci; Denisa Predeţeanu; Carmen Ginghina; C Tănăsescu Journal: Rom J Intern Med Date: 2010
Authors: I Akpinar; M R Sayin; Y C Gursoy; T Karabag; E Kucuk; M C Buyukuysal; M Aydin; I C Haznedaroglu Journal: Herz Date: 2013-04-12 Impact factor: 1.443
Authors: Iolanda Santimone; Augusto Di Castelnuovo; Amalia De Curtis; Maria Spinelli; Daniela Cugino; Francesco Gianfagna; Francesco Zito; Maria Benedetta Donati; Chiara Cerletti; Giovanni de Gaetano; Licia Iacoviello Journal: Haematologica Date: 2011-05-05 Impact factor: 9.941
Authors: Daniel Aletaha; Valerie P K Nell; Tanja Stamm; Martin Uffmann; Stephan Pflugbeil; Klaus Machold; Josef S Smolen Journal: Arthritis Res Ther Date: 2005-04-07 Impact factor: 5.156
Authors: D Aletaha; R Landewe; T Karonitsch; J Bathon; M Boers; C Bombardier; S Bombardieri; H Choi; B Combe; M Dougados; P Emery; J Gomez-Reino; E Keystone; G Koch; T K Kvien; E Martin-Mola; M Matucci-Cerinic; K Michaud; J O'Dell; H Paulus; T Pincus; P Richards; L Simon; J Siegel; J S Smolen; T Sokka; V Strand; P Tugwell; D van der Heijde; P van Riel; S Vlad; R van Vollenhoven; M Ward; M Weinblatt; G Wells; B White; F Wolfe; B Zhang; A Zink; D Felson Journal: Arthritis Rheum Date: 2008-10-15
Authors: Kerstin Dürholz; Eva Schmid; Michael Frech; Vugar Azizov; Nadine Otterbein; Sébastien Lucas; Manfred Rauh; Georg Schett; Heiko Bruns; Mario M Zaiss Journal: Front Immunol Date: 2022-07-08 Impact factor: 8.786
Authors: Lisandra Torres Hartmann; Ana Paula Alegretti; Alice Beatriz Mombach Pinheiro Machado; Eduardo Ferreira Martins; Rafael Mendonça da Silva Chakr; Andrese Aline Gasparin; Odirlei André Monticielo Journal: Open Rheumatol J Date: 2018-08-31