Literature DB >> 27708115

Changing Clinician Practices and Attitudes Regarding the Use of Antiretroviral Therapy for HIV Treatment and Prevention.

Kate Buchacz1, Jennifer Farrior2, Geetha Beauchamp3, Laura McKinstry3, Ann E Kurth4, Barry S Zingman5, Fred M Gordin6, Deborah Donnell3, Kenneth H Mayer7, Wafaa M El-Sadr8, Bernard Branson1.   

Abstract

As part of the HPTN 065 study in the Bronx, New York and Washington, the authors, we surveyed clinicians to assess for shifts in their practices and attitudes around HIV treatment and prevention. Antiretroviral therapy (ART)-prescribing clinicians at 39 HIV care sites were offered an anonymous Web-based survey at baseline (2010-2011) and at follow-up (2013). The 165 respondents at baseline and 141 respondents at follow-up had similar characteristics-almost 60% were female, median age was 47 years, two-thirds were physicians, and nearly 80% were HIV specialists. The percentage who reported recommending ART irrespective of CD4 count was higher at follow-up (15% versus 68%), as was the percentage who would initiate ART earlier for patients having unprotected sex with partners of unknown HIV status (64% versus 82%), and for those in HIV-discordant partnerships (75% versus 87%). In line with changing HIV treatment guidelines during 2010 to 2013, clinicians increasingly supported early ART for treatment and prevention.

Entities:  

Keywords:  ART; HIV prevention; clinician survey; early antiretroviral therapy; test and treat

Mesh:

Substances:

Year:  2016        PMID: 27708115      PMCID: PMC5621922          DOI: 10.1177/2325957416671410

Source DB:  PubMed          Journal:  J Int Assoc Provid AIDS Care        ISSN: 2325-9574


  28 in total

1.  Enhancing surveys of health care professionals: a meta-analysis of techniques to improve response.

Authors:  Young Ik Cho; Timothy P Johnson; Jonathan B Vangeest
Journal:  Eval Health Prof       Date:  2013-09       Impact factor: 2.651

2.  Single Viral Load Measurements Overestimate Stable Viral Suppression Among HIV Patients in Care: Clinical and Public Health Implications.

Authors:  Gary Marks; Unnati Patel; Michael J Stirratt; Michael J Mugavero; William C Mathews; Thomas P Giordano; Nicole Crepaz; Lytt I Gardner; Cynthia Grossman; Jessica Davila; Meg Sullivan; Charles E Rose; Christine OʼDaniels; Allan Rodriguez; Andrew J Wawrzyniak; Matthew R Golden; Shireesha Dhanireddy; Jacqueline Ellison; Mari-Lynn Drainoni; Lisa R Metsch; Edward R Cachay
Journal:  J Acquir Immune Defic Syndr       Date:  2016-10-01       Impact factor: 3.731

3.  Acceptability of home self-tests for HIV in New York City, 2006.

Authors:  Julie E Myers; Sara Bodach; Blayne H Cutler; Colin W Shepard; Christopher Philippou; Bernard M Branson
Journal:  Am J Public Health       Date:  2014-10-16       Impact factor: 9.308

Review 4.  Rapid HIV self-testing: long in coming but opportunities beckon.

Authors:  Julie E Myers; Wafaa M El-Sadr; Allison Zerbe; Bernard M Branson
Journal:  AIDS       Date:  2013-07-17       Impact factor: 4.177

5.  Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection.

Authors:  Jens D Lundgren; Abdel G Babiker; Fred Gordin; Sean Emery; Birgit Grund; Shweta Sharma; Anchalee Avihingsanon; David A Cooper; Gerd Fätkenheuer; Josep M Llibre; Jean-Michel Molina; Paula Munderi; Mauro Schechter; Robin Wood; Karin L Klingman; Simon Collins; H Clifford Lane; Andrew N Phillips; James D Neaton
Journal:  N Engl J Med       Date:  2015-07-20       Impact factor: 91.245

6.  U.S. trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte cell counts among HIV-infected persons, 2000 to 2008.

Authors:  Keri N Althoff; Kate Buchacz; H Irene Hall; Jinbing Zhang; David B Hanna; Peter Rebeiro; Stephen J Gange; Richard D Moore; Mari M Kitahata; Kelly A Gebo; Jeffrey Martin; Amy C Justice; Michael A Horberg; Robert S Hogg; Timothy R Sterling; Angela Cescon; Marina B Klein; Jennifer E Thorne; Heidi M Crane; Michael J Mugavero; Sonia Napravnik; Gregory D Kirk; Lisa P Jacobson; John T Brooks
Journal:  Ann Intern Med       Date:  2012-09-04       Impact factor: 25.391

Review 7.  HIV treatment as prevention: natural experiments highlight limits of antiretroviral treatment as HIV prevention.

Authors:  David P Wilson
Journal:  PLoS Med       Date:  2012-07-10       Impact factor: 11.069

8.  A mathematical model of comprehensive test-and-treat services and HIV incidence among men who have sex with men in the United States.

Authors:  Stephen W Sorensen; Stephanie L Sansom; John T Brooks; Gary Marks; Elizabeth M Begier; Kate Buchacz; Elizabeth A Dinenno; Jonathan H Mermin; Peter H Kilmarx
Journal:  PLoS One       Date:  2012-02-10       Impact factor: 3.240

9.  Trends in AIDS Deaths, New Infections and ART Coverage in the Top 30 Countries with the Highest AIDS Mortality Burden; 1990-2013.

Authors:  Reuben Granich; Somya Gupta; Bradley Hersh; Brian Williams; Julio Montaner; Benjamin Young; José M Zuniga
Journal:  PLoS One       Date:  2015-07-06       Impact factor: 3.240

10.  Closing the gap: increases in life expectancy among treated HIV-positive individuals in the United States and Canada.

Authors:  Hasina Samji; Angela Cescon; Robert S Hogg; Sharada P Modur; Keri N Althoff; Kate Buchacz; Ann N Burchell; Mardge Cohen; Kelly A Gebo; M John Gill; Amy Justice; Gregory Kirk; Marina B Klein; P Todd Korthuis; Jeff Martin; Sonia Napravnik; Sean B Rourke; Timothy R Sterling; Michael J Silverberg; Stephen Deeks; Lisa P Jacobson; Ronald J Bosch; Mari M Kitahata; James J Goedert; Richard Moore; Stephen J Gange
Journal:  PLoS One       Date:  2013-12-18       Impact factor: 3.240

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  5 in total

1.  Expanding Hospital Human Immunodeficiency Virus Testing in the Bronx, New York and Washington, District of Columbia: Results From the HPTN 065 Study.

Authors:  Bernard M Branson; Pollyanna R Chavez; Brett Hanscom; Elizabeth Greene; Laura McKinstry; Kate Buchacz; Geetha Beauchamp; Theresa Gamble; Barry S Zingman; Edward Telzak; Tammey Naab; Lisa Fitzpatrick; Wafaa M El-Sadr
Journal:  Clin Infect Dis       Date:  2018-05-02       Impact factor: 9.079

2.  Development of an HIV Testing Dashboard to Complement the HIV Care Continuum Among MSM, PWID, and Heterosexuals in Washington, DC, 2007-2015.

Authors:  Rudy Patrick; Alan Greenberg; Manya Magnus; Jenevieve Opoku; Michael Kharfen; Irene Kuo
Journal:  J Acquir Immune Defic Syndr       Date:  2017-07-01       Impact factor: 3.731

3.  Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, link-to-care, plus treat approach for HIV prevention in the United States.

Authors:  Theresa Gamble; Bernard Branson; Deborah Donnell; H Irene Hall; Georgette King; Blayne Cutler; Shannon Hader; David Burns; Jason Leider; Angela Fulwood Wood; Kevin G Volpp; Kate Buchacz; Wafaa M El-Sadr
Journal:  Clin Trials       Date:  2017-06-19       Impact factor: 2.486

4.  Viremia Trajectories of HIV in HIV-Positive Women in the United States, 1994-2017.

Authors:  Seble G Kassaye; Cuiwei Wang; Joanne Michelle F Ocampo; Tracey E Wilson; Kathryn Anastos; Mardge Cohen; Ruth M Greenblatt; Margaret A Fischl; Igho Otofukun; Adaora Adimora; Mirjam-Colette Kempf; Gerald B Sharp; Mary Young; Michael Plankey
Journal:  JAMA Netw Open       Date:  2019-05-03

5.  Implementation of "Treat-all" at adult HIV care and treatment sites in the Global IeDEA Consortium: results from the Site Assessment Survey.

Authors:  Ellen Brazier; Fernanda Maruri; Stephany N Duda; Olga Tymejczyk; C William Wester; Geoffrey Somi; Jeremy Ross; Aimee Freeman; Morna Cornell; Armel Poda; Beverly S Musick; Fujie Zhang; Keri N Althoff; Catrina Mugglin; April D Kimmel; Marcel Yotebieng; Denis Nash
Journal:  J Int AIDS Soc       Date:  2019-07       Impact factor: 5.396

  5 in total

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