Literature DB >> 27703497

Chronic myelocytic leukemic fundus lesion: A case report.

Le Wen Xu1, Yinghua Zhang1, Yan Liu1, Yan Ding1.   

Abstract

The current study reports a case of a patient with a chronic myelocytic leukemic fundus lesion, initially diagnosed in the Department of Ophthalmology, Rizhao People's Hospital (Rizhao, China). A male, 23-years-of-age, presented with a dark shadow in the front of the right eye, accompanied with blurred vision for 3 days (visual acuity of right eye, 0.4; visual acuity of left eye, 0.6). In addition, the patient had experienced gingival bleeding for 2 years, and recurrent upper respiratory infections for 1 year. A fundus examination revealed mild binocular papillary edema, dilated and tortuous veins, and the retina exhibited large quantities of scattered and dark red bleeding spots. The bleeding spots had white spots in the center, which exhibited typical Roth spots, whilst routine blood examination, abdominal ultrasound, marrow biopsy and other laboratory tests confirmed the diagnosis of chronic myelogenous leukemia. Patients with leukemia typically present with initial symptoms that include fever, fatigue, anemia and hepatosplenomegaly, and a diagnosis as a result of eye-related symptoms is rare, rendering the present case unique.

Entities:  

Keywords:  chronic myelocytic leukemia; fundus lesion; young male

Year:  2016        PMID: 27703497      PMCID: PMC5038885          DOI: 10.3892/etm.2016.3577

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  14 in total

1.  White-centred retinal haemorrhages (Roth spots).

Authors:  R Ling; B James
Journal:  Postgrad Med J       Date:  1998-10       Impact factor: 2.401

2.  Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib.

Authors:  Carlo Gambacorti-Passerini; Laura Antolini; François-Xavier Mahon; Francois Guilhot; Michael Deininger; Carmen Fava; Arnon Nagler; Chiara Maria Della Casa; Enrica Morra; Elisabetta Abruzzese; Anna D'Emilio; Fabio Stagno; Philipp le Coutre; Rafael Hurtado-Monroy; Valeria Santini; Bruno Martino; Fabrizio Pane; Andrea Piccin; Pilar Giraldo; Sarit Assouline; Muheez A Durosinmi; Onno Leeksma; Enrico Maria Pogliani; Miriam Puttini; Eunjung Jang; Josy Reiffers; Maria Grazia Valsecchi; Dong-Wook Kim
Journal:  J Natl Cancer Inst       Date:  2011-03-21       Impact factor: 13.506

3.  Relapsing acute lymphoblastic leukemia presenting with a rapidly enlarging and vision-threatening orbital mass.

Authors:  Ivan Vrcek; Katie Finnerty; Patrick Ford; Robert N Hogan; Ronald Mancini
Journal:  Int Ophthalmol       Date:  2015-01-14       Impact factor: 2.031

4.  Simultaneous bilateral central retinal vein occlusion associated with anticardiolipin antibodies in leukemia.

Authors:  N A Al-Abdulla; J T Thompson; S E LaBorwit
Journal:  Am J Ophthalmol       Date:  2001-08       Impact factor: 5.258

5.  Retinal abnormalities in newly diagnosed adult acute myeloid leukemia.

Authors:  G Specchia; F Albano; S Guerriero; C Buquicchio; L Pomes; D Pastore; P Carluccio; N Delle Noci; V Liso
Journal:  Acta Haematol       Date:  2001       Impact factor: 2.195

Review 6.  Molecular biology of bcr-abl1-positive chronic myeloid leukemia.

Authors:  Alfonso Quintás-Cardama; Jorge Cortes
Journal:  Blood       Date:  2008-09-30       Impact factor: 22.113

7.  Retinopathy in acute leukaemia at initial diagnosis: correlation of fundus lesions and haematological parameters.

Authors:  S C Reddy; N Jackson
Journal:  Acta Ophthalmol Scand       Date:  2004-02

Review 8.  Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet.

Authors:  Michele Baccarani; Jorge Cortes; Fabrizio Pane; Dietger Niederwieser; Giuseppe Saglio; Jane Apperley; Francisco Cervantes; Michael Deininger; Alois Gratwohl; François Guilhot; Andreas Hochhaus; Mary Horowitz; Timothy Hughes; Hagop Kantarjian; Richard Larson; Jerald Radich; Bengt Simonsson; Richard T Silver; John Goldman; Rudiger Hehlmann
Journal:  J Clin Oncol       Date:  2009-11-02       Impact factor: 44.544

9.  Visual Disturbance as the first Symptom of Chronic Myeloid Leukemia.

Authors:  Philemon K Huang; Srinivasan Sanjay
Journal:  Middle East Afr J Ophthalmol       Date:  2011-10
View more
  1 in total

1.  Miliary microaneurysms: An angiographic biomarker of leukemic retinopathy?

Authors:  Ankush Kawali; Padmamalini Mahendradas; Sanjay Srinivasan; Rohit Shetty
Journal:  Indian J Ophthalmol       Date:  2020-09       Impact factor: 1.848

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.