Literature DB >> 27695528

Management of equivocal (early) Fournier's gangrene.

Mohamed El-Shazly1, Mohamed Aziz2, Hamdy Aboutaleb2, Shady Salem2, Eid El-Sherif2, Mohamed Selim2, Mohamed Sultan2, Mohamed Omar2, Tarek Abd Elbaky2, Fouad Zanaty2, Talal Alenezi3, Abdelazeem Ghobashi3, Adel Allam3.   

Abstract

BACKGROUND: Fournier's gangrene (FG) is an acute progressive necrotizing fasciitis of the genital area and perineum with possible extension to the abdominal wall. Surgical debridement is the gold standard management modality of established patients. Equivocal (early) FG represents a challenge in diagnosis. The objective of this study was to compare conservative management and early exploration in cases of equivocal (early) FG.
METHODS: This was an observational study where data of all patients diagnosed as early FG in our departments over 4 years (2011-2015) were enrolled. Patients were divided into two groups: group 1 with conservative treatment, and group 2 managed with urgent exploration with longitudinal hemiscrotal incision starting from external inguinal ring. All patients' demographics, vital signs, laboratory finding and clinical findings were reported.
RESULTS: A total of 28 patients were enrolled in the study. Group 1 was managed with conservative treatment (17 patients) and group 2 underwent urgent exploration (11 patients). Overall, four patients (23.5%) out of 17 patients of group 1 showed a good response to conservative management without any surgical debridement. A total of 13 patients (76.5%) developed gangrenous discoloration and needed surgical debridement later. In group 2, four patients (36.4%) underwent scrotal exploration and release incision only without debridement and showed an excellent clinical outcome. A total of four patients (36.4%) underwent debridement with excision of doubtful deep subcutaneous and fascial tissues. The remaining three patients (27.2%) underwent debridement of necrotic fascia. The hospital stay was significantly shorter in group 2 patients than group 1 (7.5 ± 3.75 versus 13.4 ± 5.19 days p < 0.05). The mean number of debridement sessions was 3.74 ± 0.69 in group 1 versus 1.82 ± 0.34 in group 2.
CONCLUSIONS: Early exploration and debridement in equivocal (early) FG has a better clinical outcome with reduced hospital stay and number of debridement sessions than conservative treatment with delayed debridement.

Entities:  

Keywords:  Fournier; early; gangrene; management

Year:  2016        PMID: 27695528      PMCID: PMC5004234          DOI: 10.1177/1756287216655673

Source DB:  PubMed          Journal:  Ther Adv Urol        ISSN: 1756-2872


  15 in total

1.  The microbiology of necrotizing soft tissue infections.

Authors:  D Elliott; J A Kufera; R A Myers
Journal:  Am J Surg       Date:  2000-05       Impact factor: 2.565

Review 2.  Fournier's gangrene.

Authors:  Emilio Morpurgo; Susan Galandiuk
Journal:  Surg Clin North Am       Date:  2002-12       Impact factor: 2.741

Review 3.  Fournier's gangrene and its emergency management.

Authors:  A Thwaini; A Khan; A Malik; J Cherian; J Barua; I Shergill; K Mammen
Journal:  Postgrad Med J       Date:  2006-08       Impact factor: 2.401

4.  Fournier's gangrene: a review of 43 reconstructive cases.

Authors:  Pedro Costa Ferreira; Jorge Cruz Reis; José Manuel Amarante; Álvaro Catarino Silva; Carlos José Pinho; Isabel Castro Oliveira; Pedro Natividade da Silva
Journal:  Plast Reconstr Surg       Date:  2007-01       Impact factor: 4.730

Review 5.  Fournier's gangrene.

Authors:  S S Laucks
Journal:  Surg Clin North Am       Date:  1994-12       Impact factor: 2.741

Review 6.  Fournier's gangrene: a review of 1726 cases.

Authors:  N Eke
Journal:  Br J Surg       Date:  2000-06       Impact factor: 6.939

7.  Causes, presentation and survival of fifty-seven patients with necrotizing fasciitis of the male genitalia.

Authors:  M D Clayton; J E Fowler; R Sharifi; R K Pearl
Journal:  Surg Gynecol Obstet       Date:  1990-01

8.  Impact of immunodeficiency virus (HIV) on Fournier's gangrene: observations in Zambia.

Authors:  B Elem; P Ranjan
Journal:  Ann R Coll Surg Engl       Date:  1995-07       Impact factor: 1.891

Review 9.  [Fournier's gangrene: anatomo-clinical features in adults and children. Therapy update].

Authors:  A Rodríguez Alonso; M D Pérez García; A Núñez López; A Ojea Calvo; A Alonso Rodrigo; B Rodríguez Iglesias; J M Barros Rodríguez; J Benavente Delgado; J L Nogueira March
Journal:  Actas Urol Esp       Date:  2000-04       Impact factor: 0.994

10.  Fournier's Gangrene: Current Practices.

Authors:  M N Mallikarjuna; Abhishek Vijayakumar; Vijayraj S Patil; B S Shivswamy
Journal:  ISRN Surg       Date:  2012-12-03
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  3 in total

1.  Fournier's gangrene: a modern analysis of predictors of outcomes.

Authors:  Jeffrey D Sparenborg; Jacob A Brems; Andrew M Wood; Jonathan J Hwang; Krishnan Venkatesan
Journal:  Transl Androl Urol       Date:  2019-08

Review 2.  Practical Review of the Current Management of Fournier's Gangrene.

Authors:  Maria T Huayllani; Amandip S Cheema; Matthew J McGuire; Jeffrey E Janis
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-03-14

Review 3.  Fournier's Gangrene: A Coexistence or Consanguinity of SGLT-2 Inhibitor Therapy.

Authors:  Tutul Chowdhury; Nicole Gousy; Amulya Bellamkonda; Jui Dutta; Chowdhury F Zaman; Ummul B Zakia; Tasniem Tasha; Priyata Dutta; Padmaja Deb Roy; Adriana M Gomez; Arjun Mainali
Journal:  Cureus       Date:  2022-08-08
  3 in total

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