Literature DB >> 27692705

Extreme Response to High-dose Testosterone in BRCA2- and ATM-mutated Prostate Cancer.

Benjamin A Teply1, Sushant Kachhap1, Mario A Eisenberger1, Samuel R Denmeade2.   

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Year:  2016        PMID: 27692705      PMCID: PMC5808412          DOI: 10.1016/j.eururo.2016.09.020

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


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  14 in total

1.  Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts.

Authors:  Hung-Ming Lam; Holly M Nguyen; Mark P Labrecque; Lisha G Brown; Ilsa M Coleman; Roman Gulati; Bryce Lakely; Daniel Sondheim; Payel Chatterjee; Brett T Marck; Alvin M Matsumoto; Elahe A Mostaghel; Michael T Schweizer; Peter S Nelson; Eva Corey
Journal:  Eur Urol       Date:  2019-06-19       Impact factor: 20.096

Review 2.  Targeting the androgen receptor and overcoming resistance in prostate cancer.

Authors:  David J Einstein; Seiji Arai; Steven P Balk
Journal:  Curr Opin Oncol       Date:  2019-05       Impact factor: 3.645

3.  Molecular determinants of response to high-dose androgen therapy in prostate cancer.

Authors:  Michael D Nyquist; Alexandra Corella; Osama Mohamad; Ilsa Coleman; Arja Kaipainen; Daniel A Kuppers; Jared M Lucas; Patrick J Paddison; Stephen R Plymate; Peter S Nelson; Elahe A Mostaghel
Journal:  JCI Insight       Date:  2019-10-03

4.  Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of Castration-resistant Prostate Cancer.

Authors:  Michael T Schweizer; Emmanuel S Antonarakis; Samuel R Denmeade
Journal:  Eur Urol       Date:  2017-03-29       Impact factor: 20.096

Review 5.  Treatment strategies for DNA repair-deficient prostate cancer.

Authors:  Benjamin A Teply; Emmanuel S Antonarakis
Journal:  Expert Rev Clin Pharmacol       Date:  2017-06-12       Impact factor: 5.045

6.  Supraphysiologic Testosterone Induces Ferroptosis and Activates Immune Pathways through Nucleophagy in Prostate Cancer.

Authors:  Rajendra Kumar; Janet Mendonca; Olutosin Owoyemi; Kavya Boyapati; Naiju Thomas; Suthicha Kanacharoen; Max Coffey; Deven Topiwala; Carolina Gomes; Busra Ozbek; Tracy Jones; Marc Rosen; Liang Dong; Sadie Wiens; W Nathaniel Brennen; John T Isaacs; Angelo M De Marzo; Mark C Markowski; Emmanuel S Antonarakis; David Z Qian; Kenneth J Pienta; Drew M Pardoll; Michael A Carducci; Samuel R Denmeade; Sushant K Kachhap
Journal:  Cancer Res       Date:  2021-10-13       Impact factor: 13.312

7.  Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study.

Authors:  Benjamin A Teply; Hao Wang; Brandon Luber; Rana Sullivan; Irina Rifkind; Ashley Bruns; Avery Spitz; Morgan DeCarli; Victoria Sinibaldi; Caroline F Pratz; Changxue Lu; John L Silberstein; Jun Luo; Michael T Schweizer; Charles G Drake; Michael A Carducci; Channing J Paller; Emmanuel S Antonarakis; Mario A Eisenberger; Samuel R Denmeade
Journal:  Lancet Oncol       Date:  2017-12-14       Impact factor: 41.316

Review 8.  Prognostic and predictive biomarkers in prostate cancer: latest evidence and clinical implications.

Authors:  Naoki Terada; Shusuke Akamatsu; Takashi Kobayashi; Takahiro Inoue; Osamu Ogawa; Emmanuel S Antonarakis
Journal:  Ther Adv Med Oncol       Date:  2017-07-05       Impact factor: 8.168

9.  Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer.

Authors:  Emmanuel S Antonarakis; Tamara L Lotan; Harsimar Kaur; Daniela C Salles; Sanjana Murali; Jessica L Hicks; Minh Nguyen; Colin C Pritchard; Angelo M De Marzo; Jerry S Lanchbury; Bruce J Trock; William B Isaacs; Kirsten M Timms
Journal:  Clin Cancer Res       Date:  2020-07-21       Impact factor: 12.531

Review 10.  Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions.

Authors:  Osama S Mohammad; Michael D Nyquist; Michael T Schweizer; Stephen P Balk; Eva Corey; Stephen Plymate; Peter S Nelson; Elahe A Mostaghel
Journal:  Cancers (Basel)       Date:  2017-12-06       Impact factor: 6.639

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