Lara A Treviño1, Matthew W Ruble1, Kenneth Treviño1, Lawrence M Weinstein1, Dana P Gresky1. 1. Dr. Lara Treviño and Dr. Gresky are with the Department of Clinical Analytics, Humana Inc., Irving, Texas (e-mail: l trevino@humana.com ). Dr. Ruble and Dr. Weinstein are with the Department of Medical Affairs, Humana Behavioral Health, Irving. Dr. Kenneth Treviño is in private practice in Dallas.
Abstract
OBJECTIVE: The purpose of this study was to describe the prescribing practices of clinicians for patients with major depressive disorder (MDD). METHODS: This population-based, descriptive study of insured patients (N=54,107) identified people who were 18 years or older, had a claim for MDD, had at least one prescription for an antidepressant medication in 2013, and had continuous insurance coverage during the study period. Prescription claims were evaluated to determine the most commonly prescribed antidepressant medication and most common dose. RESULTS: The three most commonly prescribed antidepressant medications were citalopram (N=11,995, 22.2%), sertraline (N=10,791, 19.9%), and trazodone (N=9,501, 17.6%). The most common daily doses were 20 mg citalopram (N=6,304, 52.6%), 50 mg sertraline (N=4,173, 38.7%), and 100 mg trazodone (N=3,220, 33.9%). CONCLUSIONS: This is the first report of its kind that provides drug- and dosage-level details to demonstrate that antidepressant prescribing in clinical practice is largely within recommended guidelines.
OBJECTIVE: The purpose of this study was to describe the prescribing practices of clinicians for patients with major depressive disorder (MDD). METHODS: This population-based, descriptive study of insured patients (N=54,107) identified people who were 18 years or older, had a claim for MDD, had at least one prescription for an antidepressant medication in 2013, and had continuous insurance coverage during the study period. Prescription claims were evaluated to determine the most commonly prescribed antidepressant medication and most common dose. RESULTS: The three most commonly prescribed antidepressant medications were citalopram (N=11,995, 22.2%), sertraline (N=10,791, 19.9%), and trazodone (N=9,501, 17.6%). The most common daily doses were 20 mg citalopram (N=6,304, 52.6%), 50 mg sertraline (N=4,173, 38.7%), and 100 mg trazodone (N=3,220, 33.9%). CONCLUSIONS: This is the first report of its kind that provides drug- and dosage-level details to demonstrate that antidepressant prescribing in clinical practice is largely within recommended guidelines.
Authors: Leo R Silberbauer; Lucas Rischka; Chrysoula Vraka; Annette M Hartmann; Godber Mathis Godbersen; Cécile Philippe; Daniel Pacher; Lukas Nics; Manfred Klöbl; Jakob Unterholzner; Thomas Stimpfl; Wolfgang Wadsak; Andreas Hahn; Marcus Hacker; Dan Rujescu; Siegfried Kasper; Rupert Lanzenberger; Gregor Gryglewski Journal: Mol Psychiatry Date: 2022-09-07 Impact factor: 13.437
Authors: Mitchell E Kent; Bo Hu; Timothy M Eggleston; Ryan S Squires; Kathy A Zimmerman; Robert M Weiss; Robert D Roghair; Fang Lin; Robert A Cornell; Sarah E Haskell Journal: J Cardiovasc Pharmacol Date: 2022-08-01 Impact factor: 3.271
Authors: Mary K Lam; Lawrence T Lam; Kerryn Butler-Henderson; Jonathan King; Tahnee Clark; Peta Slocombe; Katherine Dimarco; Wendell Cockshaw Journal: Front Psychiatry Date: 2022-09-09 Impact factor: 5.435
Authors: Stephen Benjamin Peckham; Emily Ionson; Marouane Nassim; Kevin Ojha; Lena Palaniyappan; Joe Gati; Jean Thebérge; Andrea Lazosky; Mark Speechley; Imants Barušs; Soham Rej; Akshya Vasudev Journal: Trials Date: 2019-10-24 Impact factor: 2.279