Literature DB >> 27690668

Are emerging PGD2 antagonists a promising therapy class for treating asthma?

Hugo Farne1, David J Jackson1, Sebastian L Johnston1.   

Abstract

Entities:  

Keywords:  Asthma; CRTH2 antagonists; DP2 receptor antagonists; prostaglandin D2

Mesh：

Substances：

Year:  2016        PMID： 27690668     DOI： 10.1080/14728214.2016.1244262

Source DB:  PubMed          Journal:  Expert Opin Emerg Drugs        ISSN： 1472-8214            Impact factor:   4.191


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  9 in total

Review 1.  Function of secreted phospholipase A2 group-X in asthma and allergic disease.

Authors:  James D Nolin; Ryan C Murphy; Michael H Gelb; William A Altemeier; William R Henderson; Teal S Hallstrand
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-12-05       Impact factor: 4.698

2.  The Prostaglandin D2 Receptor CRTH2 Promotes IL-33-Induced ILC2 Accumulation in the Lung.

Authors:  Oyebola O Oyesola; Carolina Duque; Linda C Huang; Elisabeth M Larson; Simon P Früh; Lauren M Webb; Seth A Peng; Elia D Tait Wojno
Journal:  J Immunol       Date:  2020-01-03       Impact factor: 5.422

3.  Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonists in asthma: a systematic review and meta-analysis protocol.

Authors:  Wei Liu; Jie Min; Hongli Jiang; Bing Mao
Journal:  BMJ Open       Date:  2018-04-20       Impact factor: 2.692

Review 4.  The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation.

Authors:  Christian Domingo; Oscar Palomares; David A Sandham; Veit J Erpenbeck; Pablo Altman
Journal:  Respir Res       Date:  2018-09-29

Review 5.  Targeting cell signaling in allergic asthma.

Authors:  Seyyed Shamsadin Athari
Journal:  Signal Transduct Target Ther       Date:  2019-10-18

Review 6.  Advances and Challenges of Antibody Therapeutics for Severe Bronchial Asthma.

Authors:  Yuko Abe; Yasuhiko Suga; Kiyoharu Fukushima; Hayase Ohata; Takayuki Niitsu; Hiroshi Nabeshima; Yasuharu Nagahama; Hiroshi Kida; Atsushi Kumanogoh
Journal:  Int J Mol Sci       Date:  2021-12-22       Impact factor: 5.923

7.  Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial.

Authors:  Hugo Farne; Nicholas Glanville; Nicholas Johnson; Tata Kebadze; Julia Aniscenko; Eteri Regis; Jie Zhu; Maria-Belen Trujillo-Torralbo; Onn Min Kon; Patrick Mallia; A Toby Prevost; Michael R Edwards; Sebastian L Johnston; Aran Singanayagam; David J Jackson
Journal:  Thorax       Date:  2021-10-29       Impact factor: 9.102

Review 8.  Potential new targets for drug development in severe asthma.

Authors:  Linda Zhu; Christina E Ciaccio; Thomas B Casale
Journal:  World Allergy Organ J       Date:  2018-10-25       Impact factor: 4.084

9.  A phase 2 study to evaluate the safety, efficacy and pharmacokinetics of DP2 antagonist GB001 and to explore biomarkers of airway inflammation in mild-to-moderate asthma.

Authors:  Hector Ortega; Mary Fitzgerald; Kartik Raghupathi; Cindy-Ann Tompkins; Jinshan Shen; Karen Dittrich; Caroline Pattwell; Dave Singh
Journal:  Clin Exp Allergy       Date:  2019-11-26       Impact factor: 5.018
  9 in total

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