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Literature DB >> 27681174

Too much to differentiate: aneuploidy promotes proliferation and teratoma formation in embryonic stem cells.

Zuzana Storchová^1,2.

Abstract

Entities: Disease

Mesh：

Year: 2016 PMID： 27681174 PMCID： PMC5090212 DOI： 10.15252/embj.201695486

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

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9 in total

1. Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.

Authors: Anindita Roy; Gillian Cowan; Adam J Mead; Sarah Filippi; Georg Bohn; Aristeidis Chaidos; Oliver Tunstall; Jerry K Y Chan; Mahesh Choolani; Phillip Bennett; Sailesh Kumar; Deborah Atkinson; Josephine Wyatt-Ashmead; Ming Hu; Michael P H Stumpf; Katerina Goudevenou; David O'Connor; Stella T Chou; Mitchell J Weiss; Anastasios Karadimitris; Sten Eirik Jacobsen; Paresh Vyas; Irene Roberts
Journal: Proc Natl Acad Sci U S A Date: 2012-10-08 Impact factor: 11.205

2. Aneuploidy acts both oncogenically and as a tumor suppressor.

Authors: Beth A A Weaver; Alain D Silk; Cristina Montagna; Pascal Verdier-Pinard; Don W Cleveland
Journal: Cancer Cell Date: 2006-12-28 Impact factor: 31.743

3. Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential.

Authors: Meili Zhang; Li Cheng; Yuyan Jia; Guang Liu; Cuiping Li; Shuhui Song; Allan Bradley; Yue Huang
Journal: EMBO J Date: 2016-08-24 Impact factor: 11.598

Review 4. Short- and long-term effects of chromosome mis-segregation and aneuploidy.

Authors: Stefano Santaguida; Angelika Amon
Journal: Nat Rev Mol Cell Biol Date: 2015-08 Impact factor: 94.444

5. A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis.

Authors: Jason M Sheltzer
Journal: Cancer Res Date: 2013-09-16 Impact factor: 12.701

6. Aneuploidy causes premature differentiation of neural and intestinal stem cells.

Authors: Delphine Gogendeau; Katarzyna Siudeja; Davide Gambarotto; Carole Pennetier; Allison J Bardin; Renata Basto
Journal: Nat Commun Date: 2015-11-17 Impact factor: 14.919

7. Unique features of the transcriptional response to model aneuploidy in human cells.

Authors: Milena Dürrbaum; Anastasia Yurievna Kuznetsova; Verena Passerini; Silvia Stingele; Gabriele Stoehr; Zuzana Storchová
Journal: BMC Genomics Date: 2014-02-18 Impact factor: 3.969

8. Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo.

Authors: Sarah J Pfau; Rebecca E Silberman; Kristin A Knouse; Angelika Amon
Journal: Genes Dev Date: 2016-06-16 Impact factor: 11.361

9. Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells.

Authors: Uri Ben-David; Gal Arad; Uri Weissbein; Berhan Mandefro; Adva Maimon; Tamar Golan-Lev; Kavita Narwani; Amander T Clark; Peter W Andrews; Nissim Benvenisty; Juan Carlos Biancotti
Journal: Nat Commun Date: 2014-09-08 Impact factor: 14.919