Literature DB >> 27678037

Male contraception.

John K Amory1.   

Abstract

Although female contraceptives are very effective at preventing unintended pregnancy, some women can not use them because of health conditions or side-effects, leaving some couples without effective contraceptive options. In addition, many men wish to take active responsibility for family planning. Thus, there is a great need for male contraceptives to prevent unintended pregnancies, of which 80-90 million occur annually. At present, effective male contraceptive options are condoms and vasectomy, which are not ideal for all men. Therefore, efforts are under way to develop novel male contraceptives. This paper briefly reviews the advantages and disadvantages of condoms and vasectomies and then discusses the research directed toward development of novel methods of male contraception.
Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Spermatogenesis; condoms; novel male contraceptives; spermatozoa; testes; unintended pregnancy; vasectomy

Mesh:

Substances:

Year:  2016        PMID: 27678037      PMCID: PMC5159259          DOI: 10.1016/j.fertnstert.2016.08.036

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  81 in total

1.  Intramuscular injection of testosterone undecanoate for the treatment of male hypogonadism: phase I studies.

Authors:  H M Behre; K Abshagen; M Oettel; D Hübler; E Nieschlag
Journal:  Eur J Endocrinol       Date:  1999-05       Impact factor: 6.664

2.  Nestorone: a progestin with a unique pharmacological profile.

Authors:  N Kumar; S S Koide; Y Tsong; K Sundaram
Journal:  Steroids       Date:  2000 Oct-Nov       Impact factor: 2.668

3.  Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis.

Authors:  John K Amory; Charles H Muller; Jakob A Shimshoni; Nina Isoherranen; Jisun Paik; Jan S Moreb; David W Amory; Ryan Evanoff; Alex S Goldstein; Michael D Griswold
Journal:  J Androl       Date:  2010-08-12

4.  Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis.

Authors:  Peter Y Liu; Ronald S Swerdloff; Peter D Christenson; David J Handelsman; Christina Wang
Journal:  Lancet       Date:  2006-04-29       Impact factor: 79.321

5.  Complications of vasectomy: review of 16,000 patients.

Authors:  T Philp; J Guillebaud; D Budd
Journal:  Br J Urol       Date:  1984-12

6.  High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

Authors:  T Lufkin; D Lohnes; M Mark; A Dierich; P Gorry; M P Gaub; M LeMeur; P Chambon
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

7.  Function of retinoic acid receptor gamma in the mouse.

Authors:  D Lohnes; P Kastner; A Dierich; M Mark; M LeMeur; P Chambon
Journal:  Cell       Date:  1993-05-21       Impact factor: 41.582

8.  Vasectomy related infertility: a major and costly medical problem.

Authors:  A M Jequier
Journal:  Hum Reprod       Date:  1998-07       Impact factor: 6.918

9.  A new combination of testosterone and nestorone transdermal gels for male hormonal contraception.

Authors:  Niloufar Ilani; Mara Y Roth; John K Amory; Ronald S Swerdloff; Clint Dart; Stephanie T Page; William J Bremner; Regine Sitruk-Ware; Narender Kumar; Diana L Blithe; Christina Wang
Journal:  J Clin Endocrinol Metab       Date:  2012-07-12       Impact factor: 5.958

10.  TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN.

Authors:  S B Wolbach; P R Howe
Journal:  J Exp Med       Date:  1925-11-30       Impact factor: 14.307

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  12 in total

1.  Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

Authors:  Christina Schiza; Dimitrios Korbakis; Efstratia Panteleli; Keith Jarvi; Andrei P Drabovich; Eleftherios P Diamandis
Journal:  Mol Cell Proteomics       Date:  2018-08-10       Impact factor: 5.911

2.  Modeling the impact of novel male contraceptive methods on reductions in unintended pregnancies in Nigeria, South Africa, and the United States.

Authors:  Emily Dorman; Brian Perry; Chelsea B Polis; Lisa Campo-Engelstein; Dominick Shattuck; Aaron Hamlin; Abigail Aiken; James Trussell; David Sokal
Journal:  Contraception       Date:  2017-09-05       Impact factor: 3.375

3.  Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.

Authors:  Yan Chen; Jin-Yi Zhu; Kwon Ho Hong; David C Mikles; Gunda I Georg; Alex S Goldstein; John K Amory; Ernst Schönbrunn
Journal:  ACS Chem Biol       Date:  2018-01-03       Impact factor: 5.100

Review 4.  Emerging approaches to male contraception.

Authors:  Arthi Thirumalai; John K Amory
Journal:  Fertil Steril       Date:  2021-04-27       Impact factor: 7.490

5.  Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.

Authors:  Sarah J Martins da Silva; Sean G Brown; Keith Sutton; Louise V King; Halil Ruso; David W Gray; Paul G Wyatt; Mark C Kelly; Christopher L R Barratt; Anthony G Hope
Journal:  Hum Reprod       Date:  2017-05-01       Impact factor: 6.918

6.  CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.

Authors:  Jiang Sun; Yonggang Lu; Kaori Nozawa; Zoulan Xu; Akane Morohoshi; Julio M Castaneda; Taichi Noda; Haruhiko Miyata; Ferheen Abbasi; Hossam H Shawki; Satoru Takahashi; Darius J Devlin; Zhifeng Yu; Ryan M Matzuk; Thomas X Garcia; Martin M Matzuk; Masahito Ikawa
Journal:  Biol Reprod       Date:  2020-08-04       Impact factor: 4.285

Review 7.  Natural products in regulation of male fertility.

Authors:  Raghav Kumar Mishra; Shilpi Singh; Shio Kumar Singh
Journal:  Indian J Med Res       Date:  2018-12       Impact factor: 2.375

8.  Knowledge and Perception Regarding the Development and Acceptability of Male Contraceptives Among Pharmacists: A Mixed Sequential Method.

Authors:  Muna Barakat; Samar Thiab; Sara Thiab; Raja'a A Al-Qudah; Amal Akour
Journal:  Am J Mens Health       Date:  2022 Jan-Feb

Review 9.  Function of Retinoic Acid in Development of Male and Female Gametes.

Authors:  M Christine Schleif; Shelby L Havel; Michael D Griswold
Journal:  Nutrients       Date:  2022-03-18       Impact factor: 5.717

10.  Of mosquitoes and men: mitigating Zika risk via Men's family planning and male contraception.

Authors:  Brian T Nguyen; Robyn Schickler
Journal:  Contracept Reprod Med       Date:  2018-10-08
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