Takeshi Shinozaki1, Mitsuru Ebihara2, Satoru Iwase3, Takuhiro Yamaguchi4, Hitoshi Hirakawa5, Wataru Shimbashi6, Tomoyuki Kamijo7, Makito Okamoto8, Takeshi Beppu9, Junichiro Ohori10, Kazuto Matsuura11, Motoyuki Suzuki12, Hiroshi Nishino13, Yuichiro Sato14, Hiroto Ishiki3. 1. Department of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa tashinoz@east.ncc.go.jp. 2. Ebihara Clinic, Chigasaki. 3. Department of Palliative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo. 4. Division of Biostatistics, Tohoku University Graduate School of Medicine, Sendai. 5. Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya. 6. Department of Head and Neck Surgery, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo. 7. Department of Head and Neck Surgery, Shizuoka Cancer Center, Nagaizumicho. 8. Department of Otolaryngology, Head and Neck Surgery, Kitasato University School of Medicine, Sagamihara. 9. Department of Head and Neck Surgery, Saitama Cancer Center, Saitama. 10. Department of Otolaryngology, Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima. 11. Department of Head and Neck Surgery, Miyagi Cancer Center, Natori. 12. Department of Otolaryngology, Head and Neck Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka. 13. Department of Otolaryngology, Head and Neck Surgery, Jichi Medical University, Shimotsuke. 14. Department of Head and Neck Surgery, Niigata Cancer Center, Niigata, Japan.
Abstract
BACKGROUND: Little is known about quality of life and functional status of patients with terminally ill head and neck cancers. METHODS: We conducted a multicenter, prospective, observational study to examine quality of life and functional status in terminally ill head and neck cancer patients. RESULTS: Of the 100 patients meeting inclusion criteria, 72 were observed until death. There was no significant difference in the quality of life score between baseline and Week 3. Forty patients (54.9%) could speak and 22 patients (30.5%) could have oral intake upon study entry. Fifty-three patients (74.6%) received enteral nutrition. Twenty-six patients (36.6%) required dressing changes for fungating tumors. The route of nutritional intake (nasogastric tube vs. percutaneous gastric tube) might be predictive for the duration of hospital stay (64 vs. 21 days, P = 0.0372). CONCLUSION: There was no significant relationship between quality of life and functional status seen in this study. Feeding tube type could have the most impact on quality of life.
BACKGROUND: Little is known about quality of life and functional status of patients with terminally ill head and neck cancers. METHODS: We conducted a multicenter, prospective, observational study to examine quality of life and functional status in terminally ill head and neck cancerpatients. RESULTS: Of the 100 patients meeting inclusion criteria, 72 were observed until death. There was no significant difference in the quality of life score between baseline and Week 3. Forty patients (54.9%) could speak and 22 patients (30.5%) could have oral intake upon study entry. Fifty-three patients (74.6%) received enteral nutrition. Twenty-six patients (36.6%) required dressing changes for fungating tumors. The route of nutritional intake (nasogastric tube vs. percutaneous gastric tube) might be predictive for the duration of hospital stay (64 vs. 21 days, P = 0.0372). CONCLUSION: There was no significant relationship between quality of life and functional status seen in this study. Feeding tube type could have the most impact on quality of life.
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