Literature DB >> 27672598

Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma.

Jun-Feng Mao1, Xiao-Bo Xia1, Xiang-Bo Tang1, Xue-Yong Zhang1, Dan Wen1.   

Abstract

AIM: To investigate clinical features of optic nerve sheath meningioma (ONSM) that was misdiagnosed, and to find methods to reduce the misdiagnoses.
METHODS: Retrospective series study. Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan. 2008 to Jan. 2015 and the clinical records reviewed.
RESULTS: Patients were misdiagnosed with acute papillitis most frequently (n=17), immediately followed by optic atrophy (n=8), ischemic optic neuropathy (n=5), acute retrobulbar optic neuritis (n=5), optic disc vasculitis (n=3). For each patient, the minimum frequency of misdiagnoses was once and the maximum was 4 times. As for the lasting time of being misdiagnosed, the shortest was 1.5mo and the longest was 45mo. Twenty-one cases (84%) were once treated with glucocorticoids, and its side effects was found in seventeen patients. Twenty patients (80%) complained with varying degree of vision loss. When a definite diagnosis was made, sixteen cases (64%) showed slight exophthalmos and eighteen cases (72%) had the tubular ONSM.
CONCLUSION: ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic, and for most of these ONSMs are tubular.

Entities:  

Keywords:  clinical feature; misdiagnosis; optic nerve sheath meningioma

Year:  2016        PMID: 27672598      PMCID: PMC5028668          DOI: 10.18240/ijo.2016.09.14

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  26 in total

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2.  [Study on the characteristics of optic nerve meningiomas in medical imageology,histopathology and immunohistochemistry].

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5.  [Simulation of anterior ischemic optic neuropathy by optic nerve sheath meningioma].

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Journal:  Klin Monbl Augenheilkd       Date:  1995-09       Impact factor: 0.700

Review 6.  Long-term response to fractionated radiotherapy of presumed optic nerve sheath meningioma.

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7.  Orbital masses: CT and MRI of common vascular lesions, benign tumors, and malignancies.

Authors:  Sarah N Khan; Ali R Sepahdari
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8.  Sphenoid and optic nerve sheath meningioma revealed by recurrent brain infarctions.

Authors:  A Mourad; J-P Guichard; C Vignal; M-G Bousser; K Vahedi
Journal:  Rev Neurol (Paris)       Date:  2009-12       Impact factor: 2.607

Review 9.  Orbital neoplasms in adults: clinical, radiologic, and pathologic review.

Authors:  Tina D Tailor; Divakar Gupta; Roberta W Dalley; C Dirk Keene; Yoshimi Anzai
Journal:  Radiographics       Date:  2013-10       Impact factor: 5.333

Review 10.  Primary optic nerve sheath meningioma in children.

Authors:  Hui Bae Harold Lee; James A Garrity; J Douglas Cameron; Diego Strianese; Giulio Bonavolontà; James R Patrinely
Journal:  Surv Ophthalmol       Date:  2008 Nov-Dec       Impact factor: 6.048

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2.  Atypical acute presentation of an optic nerve sheath meningioma.

Authors:  Cole Holan; Natalie A Homer; Aliza Epstein; Vikram D Durairaj
Journal:  Am J Ophthalmol Case Rep       Date:  2020-09-29

3.  The Role of Endonasal Endoscopic Optic Nerve Decompression as the Initial Management of Primary Optic Nerve Sheath Meningiomas.

Authors:  Guillermo Maza; Somasundaram Subramaniam; Juan C Yanez-Siller; Bradley A Otto; Daniel M Prevedello; Ricardo L Carrau
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  3 in total

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