Literature DB >> 16648891

Carcinoma of the breast metastatic to the optic nerve mimicking an optic nerve sheath meningioma: case report and review of the literature.

Benjamin Fox1, Paulette Pacheco, Franco DeMonte.   

Abstract

Isolated metastatic tumors to the optic nerve are extremely rare. We describe a rare and unusual case of metastatic breast carcinoma to the optic nerve that mimicked an optic nerve sheath meningioma in its presentation due to its indolent symptom progression, initial radiological appearance, and minimal growth on serial imaging. The patient, a 46-year-old woman with a history of stable metastatic breast carcinoma, presented with progressive visual loss in her right eye over a 6-month interval. Magnetic resonance imaging revealed an enhancing lesion in the optic canal with an extension to the right anterior clinoid process and planum sphenoidale and into the right orbital apex, consistent with the presumptive diagnosis of optic nerve sheath meningioma. The tumor was resected and pathologically confirmed to be metastatic carcinoma of the breast. The clinical course, radiological features, surgical approach, and treatment strategies are reviewed.

Entities:  

Year:  2005        PMID: 16648891      PMCID: PMC1380268          DOI: 10.1055/s-2005-921935

Source DB:  PubMed          Journal:  Skull Base        ISSN: 1531-5010


  31 in total

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Journal:  Curr Opin Ophthalmol       Date:  2000-10       Impact factor: 3.761

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Journal:  Cancer       Date:  1976-09       Impact factor: 6.860

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Authors:  O Backhouse; I Simmons; A Frank; A Cassels-Brown
Journal:  Aust N Z J Ophthalmol       Date:  1998-08

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Authors:  J C Kattah; G C Chrousos; J Roberts; M Kolsky; L Zimmerman; H Manz
Journal:  Ophthalmology       Date:  1993-11       Impact factor: 12.079

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Authors:  Jerry A Shields; Carol L Shields; Richard Scartozzi
Journal:  Ophthalmology       Date:  2004-05       Impact factor: 12.079

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  8 in total

1.  Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma.

Authors:  Jun-Feng Mao; Xiao-Bo Xia; Xiang-Bo Tang; Xue-Yong Zhang; Dan Wen
Journal:  Int J Ophthalmol       Date:  2016-09-18       Impact factor: 1.779

2.  Magnetic resonance imaging of optic nerve.

Authors:  Foram Gala
Journal:  Indian J Radiol Imaging       Date:  2015 Oct-Dec

3.  Compression neuropathy caused by cancer metastasis to the optic nerve canal.

Authors:  Hiroshi Tamai; Kazuyuki Ishida; Kensuke Murakami; Norio Narita; Teiji Tominaga; Nobuo Fuse
Journal:  BMC Res Notes       Date:  2013-12-20

4.  Revisiting the "Tram-Track" sign.

Authors:  Akshay Gopinathan Nair; Veena R Iyer; Indumati Gopinathan
Journal:  Indian J Ophthalmol       Date:  2017-11       Impact factor: 1.848

5.  Isolated Unilateral Infiltrative Optic Neuropathy in a Patient with Breast Cancer

Authors:  Kaveh Abri Aghdam; Amin Zand; Mostafa Soltan Sanjari
Journal:  Turk J Ophthalmol       Date:  2019-06-27

6.  Metastatic breast carcinoma involving the optic disc.

Authors:  Christian U Kim; William A Pearce
Journal:  Am J Ophthalmol Case Rep       Date:  2020-04-05

7.  Association of optic nerve sheath lesion and brain or meningeal metastasis caused by lung cancer.

Authors:  Shuai Song; Dong Chang; Hao Li; Chunquan Liu; Yong Cui; Hongyang Li
Journal:  Thorac Cancer       Date:  2022-06-14       Impact factor: 3.223

8.  Application of optic neuro-ophthalmology imaging in latent meningeal metastases of lung cancer.

Authors:  Shuai Song; Dong Chang; Hao Li; Chunquan Liu; Hongyang Li; Yong Cui
Journal:  Thorac Cancer       Date:  2021-09-09       Impact factor: 3.500

  8 in total

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