Kimberly K Vesco1,2, Michael C Leo3, Njeri Karanja3, Matthew W Gillman4, Cindy T McEvoy5, Janet C King6, Cara L Eckhardt7, K Sabina Smith3, Nancy Perrin3, Victor J Stevens3. 1. Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA. kimberly.k.vesco@kpchr.org. 2. Department of Obstetrics & Gynecology, Kaiser Permanente Northwest, Portland, Oregon, USA. kimberly.k.vesco@kpchr.org. 3. Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA. 4. Obesity Prevention Program, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA. 5. Obesity Prevention Program, Oregon Health & Science University, Portland, Oregon, USA. 6. Pediatric and Child Health Research Program, Children's Hospital Oakland Research Institute, Oakland, California, USA. 7. School of Community Health, Portland State University, Portland, Oregon, USA.
Abstract
OBJECTIVE: This analysis was focused on 1-year maternal and infant follow-up of a randomized trial that tested a weight management intervention conducted during pregnancy. METHODS:One hundred fourteen women with obesity (mean BMI 36.7 kg/m(2) ) were randomly assigned at a mean of 15 weeks gestation to a weight management intervention or usual care control condition. The intervention ended at delivery and resulted in less gestational weight gain and a lower proportion of large-for-gestational-age newborns among intervention compared with control participants. The primary outcome at 12 months postpartum was maternal weight. Secondary outcomes included infant weight-for-age and weight-for-length z-scores. RESULTS: At 1 year, mothers in the intervention group weighed 96.3 ± 18.6 kg and those in the control group 99.7 ± 19.2 kg. There was no significant difference between groups in change in weight from randomization to 1 year postpartum (b = -0.47, 95% CI: -4.03 to 3.08). There was a significant main effect of group for infant weight-for-age z-scores (b = -0.40, 95% CI: -0.75 to -0.05) but not infant weight-for-length z-scores (b = -0.20, 95% CI: -0.59 to 0.20). CONCLUSIONS: A gestational weight management intervention did not influence maternal weight or infant weight-for-length at 1 year postpartum. Future studies may be warranted to determine whether extending prenatal interventions into the postpartum period would be beneficial for maternal and infant outcomes.
RCT Entities:
OBJECTIVE: This analysis was focused on 1-year maternal and infant follow-up of a randomized trial that tested a weight management intervention conducted during pregnancy. METHODS: One hundred fourteen women with obesity (mean BMI 36.7 kg/m(2) ) were randomly assigned at a mean of 15 weeks gestation to a weight management intervention or usual care control condition. The intervention ended at delivery and resulted in less gestational weight gain and a lower proportion of large-for-gestational-age newborns among intervention compared with control participants. The primary outcome at 12 months postpartum was maternal weight. Secondary outcomes included infant weight-for-age and weight-for-length z-scores. RESULTS: At 1 year, mothers in the intervention group weighed 96.3 ± 18.6 kg and those in the control group 99.7 ± 19.2 kg. There was no significant difference between groups in change in weight from randomization to 1 year postpartum (b = -0.47, 95% CI: -4.03 to 3.08). There was a significant main effect of group for infant weight-for-age z-scores (b = -0.40, 95% CI: -0.75 to -0.05) but not infant weight-for-length z-scores (b = -0.20, 95% CI: -0.59 to 0.20). CONCLUSIONS: A gestational weight management intervention did not influence maternal weight or infant weight-for-length at 1 year postpartum. Future studies may be warranted to determine whether extending prenatal interventions into the postpartum period would be beneficial for maternal and infant outcomes.
Authors: Zulfiqar A Bhutta; Jai K Das; Arjumand Rizvi; Michelle F Gaffey; Neff Walker; Susan Horton; Patrick Webb; Anna Lartey; Robert E Black Journal: Lancet Date: 2013-06-06 Impact factor: 79.321
Authors: Kimberly K Vesco; Njeri Karanja; Janet C King; Matthew W Gillman; Nancy Perrin; Cindy McEvoy; Cara Eckhardt; K Sabina Smith; Victor J Stevens Journal: Contemp Clin Trials Date: 2012-03-20 Impact factor: 2.226
Authors: Abdullah A Mamun; Leonie K Callaway; Michael J O'Callaghan; Gail M Williams; Jake M Najman; Rosa Alati; Alexandra Clavarino; Debbie A Lawlor Journal: BMC Pregnancy Childbirth Date: 2011-09-06 Impact factor: 3.007
Authors: Ellen A Nohr; Michael Vaeth; Jennifer L Baker; Thorkild Ia Sørensen; Jorn Olsen; Kathleen M Rasmussen Journal: Am J Clin Nutr Date: 2008-06 Impact factor: 7.045