Literature DB >> 27668531

Trichotillomania and co-occurring anxiety.

Jon E Grant1, Sarah A Redden2, Eric W Leppink2, Samuel R Chamberlain3.   

Abstract

BACKGROUND: Trichotillomania appears to be a fairly common disorder, with high rates of co-occurring anxiety disorders. Many individuals with trichotillomania also report that pulling worsens during periods of increased anxiety. Even with these clinical links to anxiety, little research has explored whether trichotillomania with co-occurring anxiety is a meaningful subtype.
METHODS: One hundred sixty-five adults with trichotillomania were examined on a variety of clinical measures including symptom severity, functioning, and comorbidity. Participants also underwent cognitive testing assessing motor inhibition and cognitive flexibility. Clinical features and cognitive functioning were compared between those with current co-occurring anxiety disorders (i.e. social anxiety, generalized anxiety disorder, panic disorder, and anxiety disorder NOS) (n=38) and those with no anxiety disorder (n=127).
RESULTS: Participants with trichotillomania and co-occurring anxiety reported significantly worse hair pulling symptoms, were more likely to have co-occurring depression, and were more likely to have a first-degree relative with obsessive compulsive disorder. Those with anxiety disorders also exhibited significantly worse motor inhibitory performance on a task of motor inhibition (stop-signal task).
CONCLUSIONS: This study suggests that anxiety disorders affect the clinical presentation of hair pulling behavior. Further research is needed to validate our findings and to consider whether treatments should be specially tailored differently for adults with trichotillomania who have co-occurring anxiety disorders, or more pronounced cognitive impairment. Copyright Â
© 2016 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2016        PMID: 27668531      PMCID: PMC5330411          DOI: 10.1016/j.comppsych.2016.09.005

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN: 0010-440X            Impact factor:   3.735


  7 in total

1.  A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania.

Authors:  Douglas W Woods; Chad T Wetterneck; Christopher A Flessner
Journal:  Behav Res Ther       Date:  2005-07-22

2.  The Trichotillomania Impact Project (TIP): exploring phenomenology, functional impairment, and treatment utilization.

Authors:  Douglas W Woods; Christopher A Flessner; Martin E Franklin; Nancy J Keuthen; Renee D Goodwin; Dan J Stein; Michael R Walther
Journal:  J Clin Psychiatry       Date:  2006-12       Impact factor: 4.384

Review 3.  The measurement of disability.

Authors:  D V Sheehan; K Harnett-Sheehan; B A Raj
Journal:  Int Clin Psychopharmacol       Date:  1996-06       Impact factor: 1.659

4.  Adult men and women with trichotillomania. A comparison of male and female characteristics.

Authors:  G A Christenson; T B MacKenzie; J E Mitchell
Journal:  Psychosomatics       Date:  1994 Mar-Apr       Impact factor: 2.386

5.  Estimated lifetime prevalence of trichotillomania in college students.

Authors:  G A Christenson; R L Pyle; J E Mitchell
Journal:  J Clin Psychiatry       Date:  1991-10       Impact factor: 4.384

6.  Characteristics of 60 adult chronic hair pullers.

Authors:  G A Christenson; T B Mackenzie; J E Mitchell
Journal:  Am J Psychiatry       Date:  1991-03       Impact factor: 18.112

7.  Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania.

Authors:  Samuel R Chamberlain; Naomi A Fineberg; Andrew D Blackwell; Trevor W Robbins; Barbara J Sahakian
Journal:  Am J Psychiatry       Date:  2006-07       Impact factor: 19.242

  7 in total
  4 in total

1.  Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania.

Authors:  Plinio C Casarotto; Caroline Biojone; Karina Montezuma; Fernando Q Cunha; Samia R L Joca; Eero Castren; Francisco S Guimaraes
Journal:  PeerJ       Date:  2018-04-17       Impact factor: 2.984

2.  Comorbidity in trichotillomania (hair-pulling disorder): A cluster analytical approach.

Authors:  Christine Lochner; Nancy J Keuthen; Erin E Curley; Esther S Tung; Sarah A Redden; Emily J Ricketts; Christopher C Bauer; Douglas W Woods; Jon E Grant; Dan J Stein
Journal:  Brain Behav       Date:  2019-11-06       Impact factor: 2.708

Review 3.  Trichotillomania is more related to Tourette disorder than to obsessive-compulsive disorder.

Authors:  Hugues Lamothe; Jean-Marc Baleyte; Luc Mallet; Antoine Pelissolo
Journal:  Braz J Psychiatry       Date:  2020 Jan-Feb       Impact factor: 2.697

Review 4.  Bidirectional Behavioral Selection in Mice: A Novel Pre-clinical Approach to Examining Compulsivity.

Authors:  Swarup Mitra; Abel Bult-Ito
Journal:  Front Psychiatry       Date:  2021-09-08       Impact factor: 4.157

  4 in total

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