Literature DB >> 27661090

Structural Analysis of Natural Products.

Jakub Přichystal1,2, Kevin A Schug3, Karel Lemr1,2, Jiří Novák1, Vladimír Havlíček1,2.   

Abstract

Current mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray diffraction are presented as structure elucidation tools for analytical chemistry of natural products. Discovering new molecular entities combined with dereplication of known organic compounds represent prerequisites for biological assays and for respective applications as pharmaceuticals or molecular markers. Liquid chromatography is briefly addressed with respect to its use in mass spectrometry- and nuclear magnetic resonance-based metabolomics studies.

Year:  2016        PMID: 27661090     DOI: 10.1021/acs.analchem.6b02386

Source DB:  PubMed          Journal:  Anal Chem        ISSN: 0003-2700            Impact factor:   6.986


  9 in total

Review 1.  Metagenomics Approaches in Discovery and Development of New Bioactive Compounds from Marine Actinomycetes.

Authors:  Gyana Prakash Mahapatra; Surabhi Raman; Suman Nayak; Sushanto Gouda; Gitishree Das; Jayanta Kumar Patra
Journal:  Curr Microbiol       Date:  2019-05-08       Impact factor: 2.188

Review 2.  Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.

Authors:  Darrell D Marshall; Robert Powers
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2017-01-11       Impact factor: 9.795

3.  Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.

Authors:  Mateusz Stoszko; Abdullah M S Al-Hatmi; Anton Skriba; Michael Roling; Enrico Ne; Raquel Crespo; Yvonne M Mueller; Mohammad Javad Najafzadeh; Joyce Kang; Renata Ptackova; Elizabeth LeMasters; Pritha Biswas; Alessia Bertoldi; Tsung Wai Kan; Elisa de Crignis; Miroslav Sulc; Joyce H G Lebbink; Casper Rokx; Annelies Verbon; Wilfred van Ijcken; Peter D Katsikis; Robert-Jan Palstra; Vladimir Havlicek; Sybren de Hoog; Tokameh Mahmoudi
Journal:  Sci Adv       Date:  2020-08-12       Impact factor: 14.136

4.  MassSpecBlocks: a web-based tool to create building blocks and sequences of nonribosomal peptides and polyketides for tandem mass spectra analysis.

Authors:  Jan Přívratský; Jiří Novák
Journal:  J Cheminform       Date:  2021-07-07       Impact factor: 5.514

Review 5.  MicroED in natural product and small molecule research.

Authors:  Emma Danelius; Steve Halaby; Wilfred A van der Donk; Tamir Gonen
Journal:  Nat Prod Rep       Date:  2020-09-17       Impact factor: 13.423

6.  Non-invasive and invasive diagnoses of aspergillosis in a rat model by mass spectrometry.

Authors:  Dominika Luptáková; Tomáš Pluháček; Miloš Petřík; Jiří Novák; Andrea Palyzová; Lucie Sokolová; Anton Škríba; Blanka Šedivá; Karel Lemr; Vladimír Havlíček
Journal:  Sci Rep       Date:  2017-11-28       Impact factor: 4.379

Review 7.  Recent Advances in Mass Spectrometry-Based Structural Elucidation Techniques.

Authors:  Xin Ma
Journal:  Molecules       Date:  2022-09-30       Impact factor: 4.927

8.  Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of Isochrysis galbana.

Authors:  Muhammad Safwan Ahamad Bustamam; Hamza Ahmed Pantami; Awanis Azizan; Khozirah Shaari; Chong Chou Min; Faridah Abas; Norio Nagao; Maulidiani Maulidiani; Sanjoy Banerjee; Fadzil Sulaiman; Intan Safinar Ismail
Journal:  Mar Drugs       Date:  2021-03-02       Impact factor: 5.118

9.  Computational Approaches and Use of Chiroptical Probes in the Absolute Configuration Assignment to Natural Products by ECD Spectroscopy: A 1,2,3-Trihydroxy-p-menthane as a Case Study.

Authors:  Giulia Marsico; Umberto Calice; Patrizia Scafato; Sandra Belviso; Antonio Evidente; Stefano Superchi
Journal:  Biomolecules       Date:  2022-03-09
  9 in total

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