Literature DB >> 27655809

The Role of CagA in the Gastric Biology of Helicobacter pylori.

Steffen Backert1, Martin J Blaser2.   

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Year:  2016        PMID: 27655809      PMCID: PMC5798256          DOI: 10.1158/0008-5472.CAN-16-1680

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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1.  DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection.

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Journal:  J Clin Invest       Date:  2012-02-06       Impact factor: 14.808

2.  An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma.

Authors:  W H Chow; M J Blaser; W J Blot; M D Gammon; T L Vaughan; H A Risch; G I Perez-Perez; J B Schoenberg; J L Stanford; H Rotterdam; A B West; J F Fraumeni
Journal:  Cancer Res       Date:  1998-02-15       Impact factor: 12.701

3.  Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology.

Authors:  J E Crabtree; J D Taylor; J I Wyatt; R V Heatley; T M Shallcross; D S Tompkins; B J Rathbone
Journal:  Lancet       Date:  1991-08-10       Impact factor: 79.321

4.  Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin.

Authors:  Burcu Kaplan-Türköz; Luisa F Jiménez-Soto; Cyril Dian; Claudia Ertl; Han Remaut; Arthur Louche; Tommaso Tosi; Rainer Haas; Laurent Terradot
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-20       Impact factor: 11.205

5.  Inverse associations of Helicobacter pylori with asthma and allergy.

Authors:  Yu Chen; Martin J Blaser
Journal:  Arch Intern Med       Date:  2007-04-23

6.  Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA.

Authors:  Manuel R Amieva; Roger Vogelmann; Antonello Covacci; Lucy S Tompkins; W James Nelson; Stanley Falkow
Journal:  Science       Date:  2003-05-30       Impact factor: 47.728

7.  Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity.

Authors:  T L Cover; C P Dooley; M J Blaser
Journal:  Infect Immun       Date:  1990-03       Impact factor: 3.441

8.  Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.

Authors:  M J Blaser; G I Perez-Perez; H Kleanthous; T L Cover; R M Peek; P H Chyou; G N Stemmermann; A Nomura
Journal:  Cancer Res       Date:  1995-05-15       Impact factor: 12.701

9.  A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.

Authors:  Xue-Song Zhang; Nicole Tegtmeyer; Leah Traube; Shawn Jindal; Guillermo Perez-Perez; Heinrich Sticht; Steffen Backert; Martin J Blaser
Journal:  PLoS Pathog       Date:  2015-02-03       Impact factor: 6.823

10.  H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model.

Authors:  James T Neal; Tracy S Peterson; Michael L Kent; Karen Guillemin
Journal:  Dis Model Mech       Date:  2013-03-01       Impact factor: 5.758

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1.  Interleukin-17C in Human Helicobacter pylori Gastritis.

Authors:  Shingo Tanaka; Hiroyuki Nagashima; Modesto Cruz; Tomohisa Uchida; Takahiro Uotani; José A Jiménez Abreu; Varocha Mahachai; Ratha-Korn Vilaichone; Thawee Ratanachu-Ek; Lotay Tshering; David Y Graham; Yoshio Yamaoka
Journal:  Infect Immun       Date:  2017-09-20       Impact factor: 3.441

Review 2.  Molecular mechanisms of the preventable causes of cancer in the United States.

Authors:  Erica A Golemis; Paul Scheet; Tim N Beck; Eward M Scolnick; David J Hunter; Ernest Hawk; Nancy Hopkins
Journal:  Genes Dev       Date:  2018-06-26       Impact factor: 11.361

Review 3.  The role of the changing human microbiome in the asthma pandemic.

Authors:  Timothy C Borbet; Xiaozhou Zhang; Anne Müller; Martin J Blaser
Journal:  J Allergy Clin Immunol       Date:  2019-12       Impact factor: 10.793

4.  Multiplex Accelerated PCR System for One-Step Helicobacter pylori cagA + Genotypes Detection: A Guide for Clinical Testing.

Authors:  Yanling Wang; Yang Li; Zhixian Luan; Yan Zhao; Peng Zhang; Cuiping Ma; Chao Shi
Journal:  Curr Microbiol       Date:  2022-06-29       Impact factor: 2.188

5.  Characterization of a novel Helicobacter pylori East Asian-type CagA ELISA for detecting patients infected with various cagA genotypes.

Authors:  Dalla Doohan; Muhammad Miftahussurur; Yuichi Matsuo; Yasutoshi Kido; Junko Akada; Takeshi Matsuhisa; Than Than Yee; Kyaw Htet; Hafeza Aftab; Ratha-Korn Vilaichone; Varocha Mahachai; Thawee Ratanachu-Ek; Lotay Tshering; Langgeng Agung Waskito; Kartika Afrida Fauzia; Tomohisa Uchida; Ari Fahrial Syam; Yudith Annisa Ayu Rezkitha; Yoshio Yamaoka
Journal:  Med Microbiol Immunol       Date:  2019-09-23       Impact factor: 3.402

6.  Prevalence and characteristics of Epstein-Barr virus-associated gastric carcinomas in Portugal.

Authors:  Paulo Figueiredo; Maximino Leitão; Célia Nogueira; Marta Mota; Rui Gradiz; Maria Augusta Cipriano; Francisco Caramelo; Hugo Cruz; Ana Alarcão; Francisco Castro E Sousa; Fernando Oliveira; Fernando Martinho; João Moura Pereira
Journal:  Infect Agent Cancer       Date:  2017-07-19       Impact factor: 2.965

7.  Helicobacter pylori infection perturbs iron homeostasis in gastric epithelial cells.

Authors:  Sebastian E Flores; Alan Aitchison; Andrew S Day; Jacqueline I Keenan
Journal:  PLoS One       Date:  2017-09-05       Impact factor: 3.240

8.  Cortactin Is Required for Efficient FAK, Src and Abl Tyrosine Kinase Activation and Phosphorylation of Helicobacter pylori CagA.

Authors:  Jakob Knorr; Irshad Sharafutdinov; Florian Fiedler; Delara Soltan Esmaeili; Manfred Rohde; Klemens Rottner; Steffen Backert; Nicole Tegtmeyer
Journal:  Int J Mol Sci       Date:  2021-06-03       Impact factor: 5.923

9.  Genotyping of Helicobacter pylori Virulence Genes cagA and vacA: Regional and National Study.

Authors:  Rania M Kishk; Nashaat M Soliman; Maha M Anani; Nader Nemr; Ayman Salem; Fawzy Attia; Amal Nooredeen Ahmed Allithy; Marwa Fouad
Journal:  Int J Microbiol       Date:  2021-06-29

Review 10.  Drosophila as a Model for Infectious Diseases.

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Journal:  Int J Mol Sci       Date:  2021-03-08       Impact factor: 5.923

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