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Literature DB >> 27650263

Current and Upcoming Therapies for Ocular Surface Chemical Injuries.

Alireza Baradaran-Rafii¹, Medi Eslani², Zeeshan Haq², Ebrahim Shirzadeh¹, Michael J Huvard², Ali R Djalilian³.

Abstract

Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular surface complications. Acute interventions are directed at decreasing the extent of the injury, suppressing inflammation, and promoting ocular surface re-epithelialization. Chronically, management involves controlling inflammation along with rehabilitation and reconstruction of the ocular surface. Future therapies aimed at inhibiting neovascularization and promoting ocular surface regeneration should provide more effective treatment options for the management of ocular chemical injuries.

Entities: Chemical Disease Gene Species

Keywords: chemical burn; cornea; limbal stem cell deficiency; ocular chemical burn; ocular surface; stem cell

Mesh：

Year: 2016 PMID： 27650263 PMCID： PMC5191942 DOI： 10.1016/j.jtos.2016.09.002

Source DB: PubMed Journal: Ocul Surf ISSN： 1542-0124 Impact factor: 5.033

222 in total

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35 in total

Review 1. An update on chemical eye burns.

Authors: Mukhtar Bizrah; Ammar Yusuf; Sajjad Ahmad
Journal: Eye (Lond) Date: 2019-05-13 Impact factor: 3.775

2. Matrix Metalloproteinase-Deactivating Contact Lens for Corneal Melting.

Authors: Chelsi Lopez; Shiwha Park; Seth Edwards; Selina Vong; Shujie Hou; Minyoung Lee; Hunter Sauerland; Jung-Jae Lee; Kyung Jae Jeong
Journal: ACS Biomater Sci Eng Date: 2019-01-04

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Authors: Luke Potts; Casie Phillips; Munok Hwang; Samuel Fulcher; Hosoon Choi
Journal: Int J Ophthalmol Date: 2019-11-18 Impact factor: 1.779

Review 4. Ocular surface inflammation impairs structure and function of meibomian gland.

Authors: Shin Mizoguchi; Hiroki Iwanishi; Reiko Arita; Kumi Shirai; Takayoshi Sumioka; Masahide Kokado; James V Jester; Shizuya Saika
Journal: Exp Eye Res Date: 2017-10 Impact factor: 3.467

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Authors: Fuyan Wang; Jun Cheng; Hualei Zhai; Yanling Dong; Hua Li; Lixin Xie
Journal: Graefes Arch Clin Exp Ophthalmol Date: 2019-11-12 Impact factor: 3.117