Literature DB >> 27649988

[Cytology of cerebrospinal fluid : Standards, importance and modern methods].

M Wick1, C C Gross2, S Isenmann3, H Strik4.   

Abstract

Cytology is an integral part of cerebrospinal fluid (CSF) analysis. It is relevant for the diagnostics and differential diagnosis of inflammatory, hemorrhagic and neoplastic central nervous system (CNS) processes. This article summarizes the recommended procedures and typical clinical patterns. In addition, modern immunocytochemical and flow cytometry methods for CSF cytology are presented. In particular, the diagnostic contribution and clinical relevance in several CNS conditions are discussed.

Entities:  

Keywords:  Cytometry; Immunophenotyping; Meningitis; Multiple sclerosis; Neoplastic processes

Mesh:

Substances:

Year:  2016        PMID: 27649988     DOI: 10.1007/s00115-016-0219-5

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  10 in total

1.  Clinical significance of occult cerebrospinal fluid involvement assessed by flow cytometry in non-Hodgkin's lymphoma patients at high risk of central nervous system disease in the rituximab era.

Authors:  Juan-Manuel Sancho; Alberto Orfao; Sandra Quijano; Olga García; Carlos Panizo; Elena Pérez-Ceballos; Guillermo Deben; Antonio Salar; Eva González-Barca; Natalia Alonso; Jose-Antonio García-Vela; Javier Capote; Francisco-Javier Peñalver; Mariano Provencio; Jesús Arias; Josefa Plaza; Dolores Caballero; Marta Morado; Evarist Feliu; Josep-Maria Ribera
Journal:  Eur J Haematol       Date:  2010-07-28       Impact factor: 2.997

2.  Automated cerebrospinal fluid cytology: limitations and reasonable applications.

Authors:  Herwig Strik; Hilmar Luthe; Ingelore Nagel; Bettina Ehrlich; Mathias Bahr
Journal:  Anal Quant Cytol Histol       Date:  2005-06       Impact factor: 0.302

3.  Automated cerebrospinal fluid cytology.

Authors:  Tanja Heller; Ingelore Nagel; Bettina Ehrlich; Mathias Bähr; Herwig Strik
Journal:  Anal Quant Cytol Histol       Date:  2008-06       Impact factor: 0.302

4.  Cerebrospinal fluid pleocytosis: pitfalls and benefits of combined analysis using cytomorphology and flow cytometry.

Authors:  Martin Bommer; Andreas Nagy; Christine Schöpflin; Sandra Pauls; Mark Ringhoffer; Mathias Schmid
Journal:  Cancer Cytopathol       Date:  2011-01-24       Impact factor: 5.284

Review 5.  Flow cytometric characterization of cerebrospinal fluid cells.

Authors:  Marieke T de Graaf; Arjen H C de Jongste; Jaco Kraan; Joke G Boonstra; Peter A E Sillevis Smitt; Jan W Gratama
Journal:  Cytometry B Clin Cytom       Date:  2011-05-12       Impact factor: 3.058

6.  Comprehensive immunophenotyping of cerebrospinal fluid cells in patients with neuroimmunological diseases.

Authors:  Sungpil Han; Yen Chih Lin; Tianxia Wu; Alan D Salgado; Ina Mexhitaj; Simone C Wuest; Elena Romm; Joan Ohayon; Raphaela Goldbach-Mansky; Adeline Vanderver; Adriana Marques; Camilo Toro; Peter Williamson; Irene Cortese; Bibiana Bielekova
Journal:  J Immunol       Date:  2014-02-07       Impact factor: 5.422

Review 7.  Immunophenotyping of cerebrospinal fluid cells in multiple sclerosis: in search of biomarkers.

Authors:  Sascha Alvermann; Christian Hennig; Olaf Stüve; Heinz Wiendl; Martin Stangel
Journal:  JAMA Neurol       Date:  2014-07-01       Impact factor: 18.302

8.  Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease.

Authors:  Gero Lueg; Catharina C Gross; Hubertus Lohmann; Andreas Johnen; Andre Kemmling; Michael Deppe; Julia Groger; Jens Minnerup; Heinz Wiendl; Sven G Meuth; Thomas Duning
Journal:  Neurobiol Aging       Date:  2014-08-23       Impact factor: 4.673

9.  Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.

Authors:  Catharina C Gross; Andreas Schulte-Mecklenbeck; Anna Rünzi; Tanja Kuhlmann; Anita Posevitz-Fejfár; Nicholas Schwab; Tilman Schneider-Hohendorf; Sebastian Herich; Kathrin Held; Matea Konjević; Marvin Hartwig; Klaus Dornmair; Reinhard Hohlfeld; Tjalf Ziemssen; Luisa Klotz; Sven G Meuth; Heinz Wiendl
Journal:  Proc Natl Acad Sci U S A       Date:  2016-05-09       Impact factor: 11.205

10.  High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: the role of flow cytometry versus cytology.

Authors:  Upendra Hegde; Armando Filie; Richard F Little; John E Janik; Nicole Grant; Seth M Steinberg; Kieron Dunleavy; Elaine S Jaffe; Andrea Abati; Maryalice Stetler-Stevenson; Wyndham H Wilson
Journal:  Blood       Date:  2004-09-09       Impact factor: 22.113

  10 in total
  4 in total

Review 1.  [Strategies for cerebrospinal fluid analysis - Integrated results report].

Authors:  M Uhr; H Tumani; P Lange
Journal:  Nervenarzt       Date:  2016-12       Impact factor: 1.214

2.  S1 guidelines "lumbar puncture and cerebrospinal fluid analysis" (abridged and translated version).

Authors:  H Tumani; H F Petereit; A Gerritzen; C C Gross; A Huss; S Isenmann; S Jesse; M Khalil; P Lewczuk; J Lewerenz; F Leypoldt; N Melzer; S G Meuth; M Otto; K Ruprecht; E Sindern; A Spreer; M Stangel; H Strik; M Uhr; J Vogelgsang; K-P Wandinger; T Weber; M Wick; B Wildemann; J Wiltfang; D Woitalla; I Zerr; T Zimmermann
Journal:  Neurol Res Pract       Date:  2020-03-16

Review 3.  Single-Cell RNA Sequencing of Cerebrospinal Fluid as an Advanced Form of Liquid Biopsy for Neurological Disorders.

Authors:  Anudeep Yekula; Jovanna Tracz; Jordina Rincon-Torroella; Tej Azad; Chetan Bettegowda
Journal:  Brain Sci       Date:  2022-06-22

Review 4.  Role and Relevance of Cerebrospinal Fluid Cells in Diagnostics and Research: State-of-the-Art and Underutilized Opportunities.

Authors:  Ferdinand Otto; Christine Harrer; Georg Pilz; Peter Wipfler; Andrea Harrer
Journal:  Diagnostics (Basel)       Date:  2021-12-30
  4 in total

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