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Literature DB >> 2764878

Determination of the structure of a novel acidic oligosaccharide with blood-group activity isolated from bovine submaxillary-gland mucin.

S M D'Arcy¹, C M Donoghue, C A Koeleman, D H Van den Eijnden, A V Savage.

Abstract

In this study we investigated the structure of an acidic fucose-containing pentasaccharide released from bovine submaxillary-gland mucin by alkaline-borohydride treatment. The structure, determined by a combination of one-dimensional and two-dimensional 1H-n.m.r. spectroscopy at 270 MHz and methylation analysis involving g.l.c.-m.s., was as follows: Fuc alpha(1----2)Gal beta(1----4)GlcNAc beta(1----3)[NeuAc alpha(2----6)]GalNAcol This pentasaccharide is a novel structure and is the first report of a blood-group-H type 2 determinant on a submaxillary-gland mucin.

Entities: Chemical Gene Species

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Year: 1989 PMID： 2764878 PMCID： PMC1138681 DOI： 10.1042/bj2600389

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

27 in total

1. Purification, composition, molecular weight, and subunit structure of ovine submaxillary mucin.

Authors: H D Hill; J A Reynolds; R L Hill
Journal: J Biol Chem Date: 1977-06-10 Impact factor: 5.157

2. High-pressure liquid chromatography of sialic acid-containing oligosaccharides.

Authors: M L Bergh; P Koppen; D H van den Eijnden
Journal: Carbohydr Res Date: 1981-08-01 Impact factor: 2.104

3. A 360-MHz 1H-NMR study of three oligosaccharides isolated from cow kappa-casein.

Authors: H van Halbeek; L Dorland; J F Vliegenthart; A M Fiat; P Jolles
Journal: Biochim Biophys Acta Date: 1980-06-26

4. Enzymatic properties of the beta-galactoside alpha 1 leads to 2 fucosyltransferase from porcine submaxillary gland.

Authors: T A Beyer; R L Hill
Journal: J Biol Chem Date: 1980-06-10 Impact factor: 5.157

5. Characterization of the primary structure and the microheterogeneity of the carbohydrate chains of porcine blood-group H substance by 500-MHz 1H-NMR spectroscopy.

Authors: H Van Halbeek; L Dorland; J F Vliegenthart; N K Kochetkov; N P Arbatsky; V A Derevitskaya
Journal: Eur J Biochem Date: 1982-09

6. Primary-structure determination of fourteen neutral oligosaccharides derived from bronchial-mucus glycoproteins of patients suffering from cystic fibrosis, employing 500-MHz 1H-NMR spectroscopy.

Authors: H Van Halbeek; L Dorland; J F Vliegenthart; W E Hull; G Lamblin; M Lhermitte; A Boersma; P Roussel
Journal: Eur J Biochem Date: 1982-09

7. Biosynthesis of the O-glycosidically linked oligosaccharide chains of fetuin. Indications for an alpha-N-acetylgalactosaminide alpha 2 leads to 6 sialyltransferase with a narrow acceptor specificity in fetal calf liver.

Authors: M L Bergh; G J Hooghwinkel; D H van den Eijnden
Journal: J Biol Chem Date: 1983-06-25 Impact factor: 5.157

8. Structure determination of oligosaccharides isolated from A+, H+ and A-H- hog-submaxillary-gland mucin glycoproteins, by 360-MHz 1H-NMR spectroscopy, permethylation analysis and mass spectrometry.

Authors: H Van Halbeek; L Dorland; J Haverkamp; G A Veldink; J F Vliegenthart; B Fournet; G Ricart; J Montreuil; W D Gathmann; D Aminoff
Journal: Eur J Biochem Date: 1981-09-01

9. Purification to homogeneity of a beta-galactoside alpha2 leads to 3 sialyltransferase and partial purification of an alpha-N-acetylgalactosaminide alpha2 leads to 6 sialyltransferase from porcine submaxillary glands.

Authors: J E Sadler; J I Rearick; J C Paulson; R L Hill
Journal: J Biol Chem Date: 1979-06-10 Impact factor: 5.157

10. Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences.

Authors: T A Beyer; J I Rearick; J C Paulson; J P Prieels; J E Sadler; R L Hill
Journal: J Biol Chem Date: 1979-12-25 Impact factor: 5.157

6 in total

1. Characterization of the major and minor mucus glycoproteins from bovine submandibular gland.

Authors: A P Corfield; C D Corfield; R W Veh; S A Wagner; J R Clamp; R Schauer
Journal: Glycoconj J Date: 1991-08 Impact factor: 2.916

2. Structural characterization of neutral oligosaccharides with blood-group A and H activity isolated from bovine submaxillary mucin.

Authors: A V Savage; S M D'Arcy; C M Donoghue
Journal: Biochem J Date: 1991-10-01 Impact factor: 3.857

6. Sialoglycoderivatives of bovine submandibular gland identified in situ by histochemical techniques combined with lectins.

Authors: G Menghi; D Accili; P Scocco; G Materazzi
Journal: Histochemistry Date: 1992