Literature DB >> 27648156

Liver resections can be performed safely without Pringle maneuver: A prospective study.

Christoph A Maurer1, Mikolaj Walensi1, Samuel A Käser1, Beat M Künzli1, René Lötscher1, Anne Zuse1.   

Abstract

AIM: To evaluate liver resections without Pringle maneuver, i.e., clamping of the portal triad.
METHODS: Between 9/2002 and 7/2013, 175 consecutive liver resections (n = 101 major anatomical and n = 74 large atypical > 5 cm) without Pringle maneuver were performed in 127 patients (143 surgeries). Accompanying, 37 wedge resections (specimens < 5 cm) and 43 radiofrequency ablations were performed. Preoperative volumetric calculation of the liver remnant preceeded all anatomical resections. The liver parenchyma was dissected by water-jet. The median central venous pressure was 4 mmHg (range: 5-14). Data was collected prospectively.
RESULTS: The median age of patients was 60 years (range: 16-85). Preoperative chemotherapy was used in 70 cases (49.0%). Liver cirrhosis was present in 6.3%, and liver steatosis of ≥ 10% in 28.0%. Blood loss was median 400 mL (range 50-5000 mL). Perioperative blood transfusions were given in 22/143 procedures (15%). The median weight of anatomically resected liver specimens was 525 g (range: 51-1850 g). One patient died postoperatively. Biliary leakages (n = 5) were treated conservatively. Temporary liver failure occurred in two patients.
CONCLUSION: Major liver resections without Pringle maneuver are feasible and safe. The avoidance of liver inflow clamping might reduce liver damage and failure, and shorten the hospital stay.

Entities:  

Keywords:  Blood loss; Liver resection; Pringle maneuver

Year:  2016        PMID: 27648156      PMCID: PMC5002500          DOI: 10.4254/wjh.v8.i24.1038

Source DB:  PubMed          Journal:  World J Hepatol


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