PURPOSE: To report the clinical findings and surgical outcomes of lamellar macular holes (LMHs) with and without lamellar hole-associated epiretinal proliferation (LHEP). METHODS: A retrospective review was performed of 73 eyes of 73 patients who underwent vitrectomy for LMH. Patients were grouped according to the presence of LHEP on preoperative spectral-domain optical coherence tomography (SD-OCT). Postoperative best-corrected visual acuity (BCVA) and OCT features were compared between LMH patients with and without LHEP. RESULTS: Lamellar hole-associated epiretinal proliferation (LHEP) was found in 15 of 73 eyes with LMHs (20.5%). The mean age was 65.0 years. The mean follow-up duration was 21.5 months. Preoperatively, eyes with LHEP were characterized by a greater hole diameter (p = 0.007), thinner fovea (p = 0.002) and greater incidence of outer retinal disruption (p < 0.001). Best-corrected visual acuity (BCVA) significantly improved after surgery in eyes without LHEP (p < 0.001), but showed no change in eyes with LHEP (p = 0.185). Initial BCVA was not different between the two groups; however, final BCVA was better in eyes without LHEP (logarithm of the minimum angle of resolution (logMAR) BCVA, 0.10 ± 0.10 versus 0.33 ± 0.40, p = 0.003). OCT evaluations of postoperative foveal configurations showed no difference between the two groups (p = 0.171). No case developed a full-thickness macular hole after surgery. CONCLUSION: There was no visual benefit after surgery in LMH patients with LHEP. Different surgical indications for LMHs may be warranted based on the presence of LHEP-associated pathology.
PURPOSE: To report the clinical findings and surgical outcomes of lamellar macular holes (LMHs) with and without lamellar hole-associated epiretinal proliferation (LHEP). METHODS: A retrospective review was performed of 73 eyes of 73 patients who underwent vitrectomy for LMH. Patients were grouped according to the presence of LHEP on preoperative spectral-domain optical coherence tomography (SD-OCT). Postoperative best-corrected visual acuity (BCVA) and OCT features were compared between LMH patients with and without LHEP. RESULTS: Lamellar hole-associated epiretinal proliferation (LHEP) was found in 15 of 73 eyes with LMHs (20.5%). The mean age was 65.0 years. The mean follow-up duration was 21.5 months. Preoperatively, eyes with LHEP were characterized by a greater hole diameter (p = 0.007), thinner fovea (p = 0.002) and greater incidence of outer retinal disruption (p < 0.001). Best-corrected visual acuity (BCVA) significantly improved after surgery in eyes without LHEP (p < 0.001), but showed no change in eyes with LHEP (p = 0.185). Initial BCVA was not different between the two groups; however, final BCVA was better in eyes without LHEP (logarithm of the minimum angle of resolution (logMAR) BCVA, 0.10 ± 0.10 versus 0.33 ± 0.40, p = 0.003). OCT evaluations of postoperative foveal configurations showed no difference between the two groups (p = 0.171). No case developed a full-thickness macular hole after surgery. CONCLUSION: There was no visual benefit after surgery in LMH patients with LHEP. Different surgical indications for LMHs may be warranted based on the presence of LHEP-associated pathology.
Authors: K Purtskhvanidze; L Balken; T Hamann; L Wöster; C von der Burchard; J Roider; Felix Treumer Journal: Graefes Arch Clin Exp Ophthalmol Date: 2018-04-06 Impact factor: 3.117
Authors: Esther Lee Kim; Adam J Weiner; Cindy Ung; Miin Roh; Jay Wang; Ivan J Lee; Natalie T Huang; Maxwell Stem; Mohammad Dahrouj; Dean Eliott; Demetrios G Vavvas; Lucy H Y Young; George A Williams; Bruce R Garretson; Ivana K Kim; Tarek S Hassan; Shizuo Mukai; Alan J Ruby; Lisa J Faia; Antonio Capone; Jason Comander; Leo A Kim; David M Wu; Kimberly A Drenser; Maria A Woodward; Jeremy D Wolfe; Yoshihiro Yonekawa Journal: Ophthalmol Retina Date: 2019-04-01
Authors: Marco Coassin; Valentina Mastrofilippo; Jay M Stewart; Andrea Fanti; Matteo Belpoliti; Luca Cimino; Alfonso Iovieno; Luigi Fontana Journal: Graefes Arch Clin Exp Ophthalmol Date: 2018-05-21 Impact factor: 3.117