Anita J Hughes1, Sarah A Redsell2, Cris Glazebrook3. 1. School of Health Sciences, University of Nottingham, Nottingham, United Kingdom; and anita.hughes@nottingham.ac.uk. 2. School of Nursing and Midwifery, Anglia Ruskin University, Cambridge, United Kingdom. 3. School of Health Sciences, University of Nottingham, Nottingham, United Kingdom; and.
Abstract
CONTEXTS: Preterm infants are at an increased risk of neurodevelopmental delay. Some studies report positive intervention effects on motor outcomes, but it is currently unclear which motor activities are most effective in the short and longer term. OBJECTIVE: The aim of the study was to identify interventions that improve the motor development of preterm infants. DATA SOURCES: An a priori protocol was agreed upon. Seventeen electronic databases from 1980 to April 2015 and gray literature sources were searched. STUDY SELECTION: Three reviewers screened the articles. DATA EXTRACTION: The outcome of interest was motor skills assessment scores. All data collection and risk of bias assessments were agreed upon by the 3 reviewers. RESULTS: Forty-two publications, which reported results from 36 trials (25 randomized controlled trials and 11 nonrandomized studies) with a total of 3484 infants, met the inclusion criteria. A meta-analysis was conducted by using standardized mean differences on 21 studies, with positive effects found at 3 months (mean 1.37; confidence interval 0.48-2.27), 6 months (0.34; 0.11-0.57), 12 months (0.73; 0.20-1.26), and 24 months (0.28; 0.07-0.49). At 3 months, there was a large and significant effect size for motor-specific interventions (2.00; 0.28-3.72) but not generic interventions (0.33; -0.03 to -0.69). Studies were not excluded on the basis of quality; therefore, heterogeneity was significant and the random-effects model was used. LIMITATIONS: Incomplete or inconsistent reporting of outcome measures limited the data available for meta-analysis beyond 24 months. CONCLUSIONS: A positive intervention effect on motor skills appears to be present up to 24 months' corrected age. There is some evidence at 3 months that interventions with specific motor components are most effective.
CONTEXTS: Preterm infants are at an increased risk of neurodevelopmental delay. Some studies report positive intervention effects on motor outcomes, but it is currently unclear which motor activities are most effective in the short and longer term. OBJECTIVE: The aim of the study was to identify interventions that improve the motor development of preterm infants. DATA SOURCES: An a priori protocol was agreed upon. Seventeen electronic databases from 1980 to April 2015 and gray literature sources were searched. STUDY SELECTION: Three reviewers screened the articles. DATA EXTRACTION: The outcome of interest was motor skills assessment scores. All data collection and risk of bias assessments were agreed upon by the 3 reviewers. RESULTS: Forty-two publications, which reported results from 36 trials (25 randomized controlled trials and 11 nonrandomized studies) with a total of 3484 infants, met the inclusion criteria. A meta-analysis was conducted by using standardized mean differences on 21 studies, with positive effects found at 3 months (mean 1.37; confidence interval 0.48-2.27), 6 months (0.34; 0.11-0.57), 12 months (0.73; 0.20-1.26), and 24 months (0.28; 0.07-0.49). At 3 months, there was a large and significant effect size for motor-specific interventions (2.00; 0.28-3.72) but not generic interventions (0.33; -0.03 to -0.69). Studies were not excluded on the basis of quality; therefore, heterogeneity was significant and the random-effects model was used. LIMITATIONS: Incomplete or inconsistent reporting of outcome measures limited the data available for meta-analysis beyond 24 months. CONCLUSIONS: A positive intervention effect on motor skills appears to be present up to 24 months' corrected age. There is some evidence at 3 months that interventions with specific motor components are most effective.
Authors: Clara Adriana Maria de Bruijn; Stefano Di Michele; Maria Luisa Tataranno; Luca Antonio Ramenghi; Andrea Rossi; Mariya Malova; Manon Benders; Agnes van den Hoogen; Jeroen Dudink Journal: Pediatr Res Date: 2022-09-09 Impact factor: 3.953
Authors: Carmen Rosa Pallás-Alonso; Begoña Loureiro; Javier De la Cruz Bértolo; Pilar García; Gemma Ginovart; Ana Jiménez; Yolanda Martín; Javier Soriano; María José Torres; Máximo Vento Journal: Acta Paediatr Date: 2018-12-14 Impact factor: 2.299
Authors: Marlene Rosager Lund Pedersen; Marianne Staal Stougaard; Bjarne Ibsen Journal: Int J Environ Res Public Health Date: 2021-11-25 Impact factor: 3.390
Authors: Jen Heng Pek; Bei Jun Yap; Ming Ying Gan; Shu Ting Tammie Seethor; Rachel Greenberg; Christoph Paul Vincent Hornik; Bobby Tan; Jan Hau Lee; Shu-Ling Chong Journal: BMJ Open Date: 2020-06-11 Impact factor: 2.692