MOTIVATION: Ancestry and Kinship Toolkit (AKT) is a statistical genetics tool for analysing large cohorts of whole-genome sequenced samples. It can rapidly detect related samples, characterize sample ancestry, calculate correlation between variants, check Mendel consistency and perform data clustering. AKT brings together the functionality of many state-of-the-art methods, with a focus on speed and a unified interface. We believe it will be an invaluable tool for the curation of large WGS datasets. AVAILABILITY AND IMPLEMENTATION: The source code is available at https://illumina.github.io/akt CONTACTS: joconnell@illumina.com or rudy.d.arthur@gmail.comSupplementary information: Supplementary data are available at Bioinformatics online.
MOTIVATION: Ancestry and Kinship Toolkit (AKT) is a statistical genetics tool for analysing large cohorts of whole-genome sequenced samples. It can rapidly detect related samples, characterize sample ancestry, calculate correlation between variants, check Mendel consistency and perform data clustering. AKT brings together the functionality of many state-of-the-art methods, with a focus on speed and a unified interface. We believe it will be an invaluable tool for the curation of large WGS datasets. AVAILABILITY AND IMPLEMENTATION: The source code is available at https://illumina.github.io/akt CONTACTS: joconnell@illumina.com or rudy.d.arthur@gmail.comSupplementary information: Supplementary data are available at Bioinformatics online.
Authors: Gavin Chapman; Julie L M Moreau; Eddie I P; Justin O Szot; Kavitha R Iyer; Hongjun Shi; Michelle X Yam; Victoria C O'Reilly; Annabelle Enriquez; Joelene A Greasby; Dimuthu Alankarage; Ella M M A Martin; Bernadette C Hanna; Matthew Edwards; Steven Monger; Gillian M Blue; David S Winlaw; Helen E Ritchie; Stuart M Grieve; Eleni Giannoulatou; Duncan B Sparrow; Sally L Dunwoodie Journal: Hum Mol Genet Date: 2020-03-13 Impact factor: 6.150
Authors: Andrew P Morgan; Jonathan J Hughes; John P Didion; Wesley J Jolley; Karl J Campbell; David W Threadgill; Francois Bonhomme; Jeremy B Searle; Fernando Pardo-Manuel de Villena Journal: Heredity (Edinb) Date: 2022-06-28 Impact factor: 3.832
Authors: Ingrid Tarr; Stephanie Hesselson; Siiri E Iismaa; Emma Rath; Steven Monger; Michael Troup; Ketan Mishra; Claire M Y Wong; Pei-Chen Hsu; Keerat Junday; David T Humphreys; David Adlam; Tom R Webb; Anna A Baranowska-Clarke; Stephen E Hamby; Keren J Carss; Nilesh J Samani; Monique Bax; Lucy McGrath-Cadell; Jason C Kovacic; Sally L Dunwoodie; Diane Fatkin; David W M Muller; Robert M Graham; Eleni Giannoulatou Journal: Circ Genom Precis Med Date: 2022-05-18
Authors: Stephen D Turner; V P Nagraj; Matthew Scholz; Shakeel Jessa; Carlos Acevedo; Jianye Ge; August E Woerner; Bruce Budowle Journal: Front Genet Date: 2022-06-30 Impact factor: 4.772
Authors: Arthur Gilly; Lorraine Southam; Daniel Suveges; Karoline Kuchenbaecker; Rachel Moore; Giorgio E M Melloni; Konstantinos Hatzikotoulas; Aliki-Eleni Farmaki; Graham Ritchie; Jeremy Schwartzentruber; Petr Danecek; Britt Kilian; Martin O Pollard; Xiangyu Ge; Emmanouil Tsafantakis; George Dedoussis; Eleftheria Zeggini Journal: Bioinformatics Date: 2019-08-01 Impact factor: 6.937
Authors: Andrew P Morgan; Nicholas F Brazeau; Billy Ngasala; Lwidiko E Mhamilawa; Madeline Denton; Mwinyi Msellem; Ulrika Morris; Dayne L Filer; Ozkan Aydemir; Jeffrey A Bailey; Jonathan B Parr; Andreas Mårtensson; Anders Bjorkman; Jonathan J Juliano Journal: Malar J Date: 2020-01-28 Impact factor: 2.979
Authors: Jared O'Connell; Taedong Yun; Meghan Moreno; Helen Li; Nadia Litterman; Alexey Kolesnikov; Elizabeth Noblin; Pi-Chuan Chang; Anjali Shastri; Elizabeth H Dorfman; Suyash Shringarpure; Adam Auton; Andrew Carroll; Cory Y McLean Journal: Commun Biol Date: 2021-11-05