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Literature DB >> 27628433

Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.

Huiping Sun^1,2, Jinghan Su¹, Qingshuo Meng¹, Qi Yin¹, Lingli Chen¹, Wangwen Gu¹, Pengcheng Zhang¹, Zhiwen Zhang¹, Haijun Yu¹, Siling Wang², Yaping Li¹.

Abstract

A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung metastasis of the breast cancer cells.

Entities: Chemical Disease

Keywords: biomimetic; cancer; chemotherapy; metastasis; nanoparticles; self-targeting

Year: 2016 PMID： 27628433 DOI： 10.1002/adma.201602173

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

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Cited

87 in total

Review 1. Recent advances in understanding oligonucleotide aptamers and their applications as therapeutic agents.

Authors: Khaled S Allemailem; Ahmad Almatroudi; Mohammed A Alsahli; Ghaiyda Talal Basfar; Faris Alrumaihi; Arshad Husain Rahmani; Amjad Ali Khan
Journal: 3 Biotech Date: 2020-11-24 Impact factor: 2.406

2. A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H₂ O₂ -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

Authors: Jinping Wang; Jingyu Sun; Wei Hu; Yuhao Wang; Tsengming Chou; Beilu Zhang; Qiang Zhang; Lei Ren; Hongjun Wang
Journal: Adv Mater Date: 2020-04-24 Impact factor: 30.849

Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.

Review 1. Recent advances in understanding oligonucleotide aptamers and their applications as therapeutic agents.

2. A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H₂ O₂ -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

3. Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.

Review 4. Engineering biological interactions on the nanoscale.

Review 5. Emerging Biomimetic Materials for Studying Tumor and Immune Cell Behavior.

6. Erythrocyte-Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization.

Review 7. Best Practices for Preclinical In Vivo Testing of Cancer Nanomedicines.

8. Advances in targeted nanotherapeutics: From bioconjugation to biomimicry.

Review 9. Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Review 10. Platelets and their biomimetics for regenerative medicine and cancer therapies.

Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.

Review 1. Recent advances in understanding oligonucleotide aptamers and their applications as therapeutic agents.

2. A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H2 O2 -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

3. Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.

Review 4. Engineering biological interactions on the nanoscale.

Review 5. Emerging Biomimetic Materials for Studying Tumor and Immune Cell Behavior.

6. Erythrocyte-Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization.

Review 7. Best Practices for Preclinical In Vivo Testing of Cancer Nanomedicines.

8. Advances in targeted nanotherapeutics: From bioconjugation to biomimicry.

Review 9. Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Review 10. Platelets and their biomimetics for regenerative medicine and cancer therapies.

2. A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H₂ O₂ -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.