Literature DB >> 27626149

Short-term effects of intravitreal dexamethasone implant (OZURDEX®) on choroidal thickness in patients with naive branch retinal vein occlusion.

Hasan Basri Arifoglu1, Necati Duru1, Orhan Altunel1, Burhan Baskan1, Bedirhan Alabay1, Mustafa Atas1.   

Abstract

PURPOSE: The objective of this study was to evaluate subfoveal choroidal thickness (SFCT) using enhanced depth imaging optical coherence tomography (EDI-OCT) in patients with naïve branch retinal vein occlusion (BRVO) before and after intravitreal dexamethasone implant (Ozurdex®) injection.
METHODS: Thirty-nine patients with unilateral BRVO and 35 healthy subjects were included in this prospective study. Choroidal thickness was evaluated by EDI-OCT at baseline and 1 month after dexamethasone implant.
RESULTS: The mean SFCT measured in 39 patients with BRVO was 299.41 ± 55.86 µm, significantly greater than that in contralateral eyes (283.76 ± 57.44 µm; p=0.009) and control eyes (276.14 ± 39.06 µm; p=0.044). The mean SFCT after the treatment was 279.64 ± 50.96 µm, significantly thinner than that before intravitreal dexamethasone therapy (p=0.004).
CONCLUSIONS: SFCT in treatment-naive BRVO eyes was significantly greater than that in contralateral eyes and healthy eyes and decreased significantly after intravitreal dexamethasone implantation.

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Year:  2016        PMID: 27626149     DOI: 10.5935/0004-2749.20160069

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  2 in total

1.  10-year fundus tessellation progression and retinal vein occlusion.

Authors:  Yan-Ni Yan; Ya-Xing Wang; Yan Yang; Liang Xu; Jie Xu; Qian Wang; Jing-Yan Yang; Wen-Jia Zhou; Wen-Bin Wei; Jost B Jonas
Journal:  Int J Ophthalmol       Date:  2018-07-18       Impact factor: 1.779

2.  Long-term Results of Ranibizumab, Dexamethasone Implant, and Triamcinolone in Macular Edema due to Branch Retinal Vein Occlusion.

Authors:  Nevin Hande Dikel; Erhan Yumusak; Nesrin Buyuktortop Gokcinar
Journal:  Beyoglu Eye J       Date:  2019-12-27
  2 in total

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