| Literature DB >> 27623946 |
Lotte Soeteman1, Job van Exel1,2, Ana Bobinac3.
Abstract
The questionnaire format applied in a CV study represents the way in which the WTP estimates are obtained. Payment scales are often used in CV studies as the questionnaire format of choice. The study summarized here analyzes the impact of the design of two payment scales (PS) on the monetary value of QALY gains. The scales differed in terms of their end-points, mid points, and coarseness. We judged the performance of the two PS against several indicators: the average WTP per QALY estimates, post-estimation uncertainty levels, the existence of mid-point concentration, and the dependency on end-points. Our results show that PS design influences respondents' WTP values. The results also suggest that a more detailed scale with a more realistic range may help respondents to elicit values closer to their "true" WTP values, hence produce higher-quality outcomes. Further research and pretesting strategies are suggested to explore and minimize the effects of PS design on WTP estimates, which may ultimately increase the quality of WTP estimates.Entities:
Keywords: Bias; Contingent valuation; Payment scale; Preferences; QALY; Uncertainty; Willingness to pay
Mesh:
Year: 2016 PMID: 27623946 PMCID: PMC5486460 DOI: 10.1007/s10198-016-0825-y
Source DB: PubMed Journal: Eur J Health Econ ISSN: 1618-7598
Fig. 1PS-5 and PS-25: intervals and value points
Summary statistics
| Variable | PS-5 | PS-25 | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Min | Max | Mean | SD | Min | Max | |
| Age (years) | 42.2 | 13.1 | 18 | 65 | 39.3 | 12.4 | 18 | 65 |
| Sex (female) | 0.49 | 0.50 | 0.51 | 0.50 | ||||
| Married (yes) | 0.62 | 0.49 | 0.55 | 0.50 | ||||
| Children (yes) | 0.55 | 0.50 | 0.46 | 0.50 | ||||
| Number of childrena | 2.07 | 0.93 | 1 | 5 | 2.06 | 1.26 | 1 | 15 |
| Higher vocational or academic education (yes) | 0.34 | 0.47 | 0.36 | 0.48 | ||||
| Employed (yes) | 0.60 | 0.49 | 0.64 | 0.48 | ||||
| Household income (€) | 2724 | 1694 | 999 | 10,000 | 2563 | 1501 | 999 | 10,000 |
| (% < €1000) | 0.12 | 0.15 | ||||||
| (% ≥ €1000 and < €2000) | 0.34 | 0.34 | ||||||
| (% ≥ €2000 and < €3500) | 0.37 | 0.37 | ||||||
| (% ≥ €3500) | 0.16 | 0.14 | ||||||
| Number of people living on household income | 4.25 | 2.72 | 1 | 13 | 4.01 | 2.53 | 1 | 13 |
| EQ-5D (Dutch tariff) | 0.85 | 0.23 | 0 | 1 | 0.85 | 0.23 | 0 | 1 |
| EQ-VAS (1–100) | 72.7 | 19.6 | 0 | 100 | 72.5 | 18.3 | 0 | 100 |
VAS visual analogue scale
aPS-5, n = 583; PS-25, n = 485
QALY gain, PS value range, and OE-WTP (monthly; in €)
| Variable | PS-5 | PS-25 |
| ||
|---|---|---|---|---|---|
| Average | SD | Average | SD | ||
| PSL,A | 36.98 | 79.18 | 115.77 | 312.75 | 0.000 |
| OE-WTP | 53.36 | 91.91 | 154.21 | 351.27 | 0.000 |
| PSU,A | 115.28 | 167.78 | 358.56 | 675.60 | 0.000 |
| Expected QALY gain | 0.087 | 0.148 | 0.096 | 0.165 | 0.054 |
| WTP per QALY (per year*) | 227,200 | 404,400 | 0.000 | ||
|
| 508 | 507 | |||
* Monthly values multiplied by 12
Results of multivariate regression analysis with Log(OE-WTP) as the dependant variable (n = 936)
| Variable | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Coefficient | SE |
| Coefficient | SE |
| Coefficient | SE |
| |
| log(expected health gaina) | 0.128 | 0.027 | 0.000 | 0.861 | 0.028 | 0.003 | 0.09 | 0.023 | 0.000 |
| Age | −0.021 | 0.004 | 0.000 | −0.199 | 0.003 | 0.000 | −0.019 | 0.003 | 0.000 |
| log(income) | 0.697 | 0.098 | 0.000 | 0.578 | 0.088 | 0.000 | 0.531 | 0.089 | 0.000 |
| Education (high = 1) | 0.146 | 0.108 | 0.177 | 0.024 | 0.031 | 0.41 | 0.032 | 0.031 | 0.295 |
| Gender (female = 1) | 0.180 | 0.101 | 0.075 | 0.141 | 0.089 | 0.115 | 0.132 | 0.089 | 0.141 |
| Payment scale (PS-25 = 1) | 0.896 | 0.100 | 0.000 | 0.917 | 0.089 | 0.000 | 0.842 | 0.165 | 0.000 |
| Constant | −1.311 | 0.769 | 0.089 | −0.735 | 0.680 | 0.281 | −0.048 | 0.687 | 0.944 |
| Risk 2 % | Omitted | ||||||||
| Risk 4 % | 0.095 | 0.126 | 0.448 | ||||||
| Risk 10 % | 0.109 | 0.132 | 0.408 | ||||||
| Risk 50 % | 0.305 | 0.124 | 0.015 | ||||||
| PS*certainty level | 0.077 | 0.167 | 0.644 | ||||||
|
| 0.172 | 0.191 | |||||||
aThe level of health risk presented in scenarios is a part of the expected QALY gain, which is a multiplication of the level of risk and the size of the health gain (or the difference between the utility weightings of the two EQ 5D health states offered in each scenario)
Frequencies table (PS-5 and PS-25)
| PS-5 | PS-25 | |||
|---|---|---|---|---|
| Freq. | % | Freq. | % | |
| Amount (already) on scale (value point) | 395 | 77.8 | 258 | 50.9 |
| Non-rounded amount (not on scale) | 47 | 9.3 | 60 | 11.8 |
| Rounded amount (not on scale) | 66 | 13.0 | 189 | 37.3 |
|
| 508 | 100 | 507 | 100 |
Fig. 2Most frequently stated maximum WTP OE, obtained following PS-5 and PS-25 (here presented on PS-5 and PS-25
Fig. 3Respondents’ WTP value gaps and related maximum OE-WTP (monthly values*) Note: L lower end of the value gap; U upper end of the value gap; A average. *To obtain yearly values, monthly values should be multiplied by 12
Fig. 4Response certainty
| Choice scenario | Health state 1 | Health state 2 | Level of risk (%) |
|---|---|---|---|
| 1 | 22222 | 11131 | 10 |
| 2 | 33232 | 33323 | 50 |
| 3 | 21312 | 12111 | 2 |
| 4 | 22323 | 21312 | 2 |
| 5 | 22323 | 12111 | 2 |
| 6 | 21232 | 32211 | 4 |
| 7 | 11112 | 22121 | 10 |
| 8 | 11122 | 22122 | 10 |
| 9 | 21323 | 22233 | 4 |
| 10 | 22331 | 21133 | 4 |
| 11 | 21111 | 12121 | 50 |
| 12 | 23232 | 32232 | 50 |
| 13 | 11312 | 11113 | 10 |
| 14 | 12311 | 11211 | 2 |
| 15 | 32311 | 12311 | 10 |
| 16 | 32311 | 11211 | 2 |
| 17 | 21111 | 12211 | 50 |
| 18 | 32313 | 32331 | 50 |
| 19 | 11211 | 22211 | 4 |
| 20 | 23313 | 11133 | 50 |
| 21 | 11121 | 22112 | 10 |
| 22 | 12223 | 13332 | 10 |
| 23 | 11312 | 11211 | 2 |
| 24 | 11332 | 11312 | 4 |
| 25 | 11332 | 11211 | 2 |
| 26 | 21222 | 33321 | 2 |
| 27 | 22222 | 13311 | 50 |
| 28 | 11112 | 22112 | 4 |
| 29 | 33212 | 32223 | 4 |