| Literature DB >> 27615273 |
Fernando Carceller1,2, Neil P Jerome3, Keiko Miyazaki3, David J Collins3, Matthew R Orton3, James A d'Arcy3, Toni Wallace4, Lucas Moreno1,2,5, Andrew D J Pearson1,2, Stergios Zacharoulis1,2, Martin O Leach3, Lynley V Marshall1,2, Dow-Mu Koh4.
Abstract
Diffusion-weighted (DW) and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) have been used as imaging biomarkers in adults with high-grade gliomas (HGGs). We incorporated free-breathing DW-MRI and DCE-MRI, at a single time point, in the routine follow-up of five children (median age 9 years, range 8-15) with histologically confirmed HGG within a prospective imaging study. It was feasible to incorporate DW-MRI and DCE-MRI in routine assessments of children with HGG. DW and DCE parameters were repeatable in paediatric HGG. Higher median ADC100-1000 significantly correlated with longer survival in our sample.Entities:
Keywords: diffusion-weighted; dynamic contrast-enhanced; functional imaging; high-grade glioma; magnetic resonance; paediatric
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Year: 2016 PMID： 27615273 DOI： 10.1002/pbc.26216
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN： 1545-5009 Impact factor: 3.167