Literature DB >> 27613547

A decade of day-case endoscopically guided stent placement in malignant oesophagogastric strictures.

L M Almond1, K Patel2, L Keast2, J Hodson3, R Nijjar2, P G Wilson4, M Richardson2, R Singhal2.   

Abstract

BACKGROUND: Self-expanding metal stents (SEMSs) are the palliative treatment of choice for rapid symptomatic relief in patients with malignant dysphagia. Increasingly endoscopically guided insertion is performed as a day case and without the need for fluoroscopic guidance. This consecutive case series reports 11-year experience of endoscopically guided SEMS insertion in a large UK specialist oesophagogastric unit.
METHODS: Patients undergoing stent insertion for malignant dysphagia between 2003 and 2014 were identified from a prospectively maintained database. Data on patient demographics, tumour characteristics, indications, technique of insertion, complications, and need for re-intervention were abstracted and then corroborated by retrospective review of electronic case records.
RESULTS: A total of 362 patients with a median age of 76 years underwent primary SEMS insertion under endoscopic guidance. Repeat endoscopic intervention was required in 26 patients within 30 days and 59 patients within 90 days of primary insertion, giving Kaplan-Meier estimated re-intervention rates of 7.7 % and 20.3 %, respectively. Higher tumours were associated with need for repeat intervention (p = 0.014). The most frequent repeat intervention was insertion of a new stent, most commonly for stent migration or tumour overgrowth. Out of 252, 222 (88.1 %) patients referred through a rapid access pathway were stented as day cases, and the 30-day readmission rate in this cohort did not differ significantly from patients stented as inpatients (p = 0.774). Three (0.8 %) patients suffered a perforation, and there was a single procedure-related death.
CONCLUSIONS: This large consecutive case series demonstrates that endoscopically guided SEMS insertion in malignant dysphagia can be performed efficiently as a day case with low complication, readmission, and re-intervention rates.

Entities:  

Keywords:  Malignant dysphagia; Oesophageal cancer; Oesophagogastric junctional cancer; Palliation; Self-expanding metal stent

Mesh:

Year:  2016        PMID: 27613547     DOI: 10.1007/s00464-016-5230-1

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  20 in total

1.  Self-expanding oesophageal stents: strategies for re-intervention.

Authors:  K McManus; I Khan; J McGuigan
Journal:  Endoscopy       Date:  2001-07       Impact factor: 10.093

Review 2.  Self-expanding metal stent insertion for inoperable esophageal carcinoma in Belfast: an audit of outcomes and literature review.

Authors:  R T Gray; M E O'Donnell; R D Scott; J A McGuigan; I Mainie
Journal:  Dis Esophagus       Date:  2011-03-18       Impact factor: 3.429

3.  Delayed complications after placement of self-expanding stents in malignant esophageal obstruction: treatment strategies and survival rate.

Authors:  Nils Homann; Maria R Noftz; Rolf D Klingenberg-Noftz; Diether Ludwig
Journal:  Dig Dis Sci       Date:  2007-06-28       Impact factor: 3.199

4.  Insertion of expandable metallic stents in esophageal cancer without fluoroscopy is safe and effective: a 5-year experience.

Authors:  Emilie A Wilkes; Lucina M Jackson; Andrew T Cole; Jan G Freeman; Andrew F Goddard
Journal:  Gastrointest Endosc       Date:  2007-05       Impact factor: 9.427

Review 5.  Interventions for dysphagia in oesophageal cancer.

Authors:  Aravamuthan Sreedharan; Keith Harris; Adrian Crellin; David Forman; Simon M Everett
Journal:  Cochrane Database Syst Rev       Date:  2009-10-07

6.  A randomized controlled clinical trial of palliative therapies for patients with inoperable esophageal cancer.

Authors:  Jonathan Shenfine; Paul McNamee; Nick Steen; John Bond; S Michael Griffin
Journal:  Am J Gastroenterol       Date:  2009-05-12       Impact factor: 10.864

7.  Incidence and distribution of distant metastases from newly diagnosed esophageal carcinoma.

Authors:  L E Quint; L M Hepburn; I R Francis; R I Whyte; M B Orringer
Journal:  Cancer       Date:  1995-10-01       Impact factor: 6.860

8.  A randomised prospective comparison of the Flamingo Wallstent and Ultraflex stent for palliation of dysphagia associated with lower third oesophageal carcinoma.

Authors:  T Sabharwal; M S Hamady; S Chui; S Atkinson; R Mason; A Adam
Journal:  Gut       Date:  2003-07       Impact factor: 23.059

Review 9.  Treatment options for esophageal strictures.

Authors:  Peter D Siersema
Journal:  Nat Clin Pract Gastroenterol Hepatol       Date:  2008-02-05

Review 10.  Interventions for dysphagia in oesophageal cancer.

Authors:  Yingxue Dai; Chaoying Li; Yao Xie; Xudong Liu; Jianxin Zhang; Jing Zhou; Xiongfei Pan; Shujuan Yang
Journal:  Cochrane Database Syst Rev       Date:  2014-10-30
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  2 in total

Review 1.  Clinical efficacy and safety of palliative esophageal stenting without fluoroscopy: a systematic review and meta-analysis.

Authors:  Saurabh Chandan; Babu P Mohan; Shahab R Khan; Neil Bhogal; Andrew Canakis; Mohammad Bilal; Amaninder S Dhaliwal; Muhammad Aziz; Harmeet S Mashiana; Shailender Singh; Wade Lee-Smith; Suresh Ponnada; Ishfaq Bhat; Douglas Pleskow
Journal:  Endosc Int Open       Date:  2020-06-16

2.  Rare malignant spindle cell sarcoma of the left atrium diagnosed with TEE: A case report.

Authors:  Yuan-Yuan Sun; Xin-Yu Wang; Guo-Ming Zhang; Xu Chen; Bo Jing; Yuan Wu; Yu Song; Mao-Long Su
Journal:  Medicine (Baltimore)       Date:  2021-03-12       Impact factor: 1.817

  2 in total

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