| Literature DB >> 27612807 |
Basil Mujokoro1, Mohsen Adabi2, Esmaeil Sadroddiny3, Mahdi Adabi4, Masood Khosravani5.
Abstract
Glioblastoma is a malignant brain tumor and leads to death in most patients. Chemotherapy is a common method for brain cancer in clinics. However, the recent advancements in the chemotherapy of brain tumors have not been efficient enough. With the advancement of nanotechnology, the used drugs can enhance chemotherapy efficiency and increase the access to brain cancers. Combination of therapeutic agents has been recently attracted great attention for glioblastoma chemotherapy. One of the early benefits of combination therapies is the high potential to provide synergistic effects and decrease adverse side effects associated with high doses of single anticancer drugs. Therefore, brain tumor treatments with combination drugs can be considered as a crucial approach for avoiding tumor growth. This review investigates current progress in nano-mediated co-delivery of therapeutic agents with focus on glioblastoma chemotherapy prognosis.Entities:
Keywords: Chemosensitizer; Chemotherapy; Co-delivery; Drug delivery; Gene therapy; Glioblastoma; Nanoparticle
Mesh：
Substances：
Year: 2016 PMID： 27612807 DOI： 10.1016/j.msec.2016.07.080
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN： 0928-4931 Impact factor: 7.328