BACKGROUND: Causes and significance of interventricular conduction disorders (IVCDs) after orthotopic heart transplantation (OHT) are still unknown. METHODS: We retrospectively researched the presence of IVCDs in 240 patients who underwent bicaval OHT in three time periods: at day 1, after 1 year, and after 3 years from OHT. To evaluate the impact of the surgical technique, a control population treated with biatrial anastomosis was used. RESULTS: The most common IVCD was right bundle branch block (RBBB). Its presence at day 1 correlated with transpulmonary gradient before OHT. Its presence after 1 year and its development correlated with a 1-month acute rejection score≥2 (p = .050 and p = .006). The incidence of RBBB was higher in the biatrial control population (40.7% vs 23.8%, p < .001). CONCLUSIONS: RBBB is the most common IVCD. Its presence can be explained by a susceptibility of the right branch to heart positioning, pressure overload, and acute rejection. IVCDs do not affect prognosis.
BACKGROUND: Causes and significance of interventricular conduction disorders (IVCDs) after orthotopic heart transplantation (OHT) are still unknown. METHODS: We retrospectively researched the presence of IVCDs in 240 patients who underwent bicaval OHT in three time periods: at day 1, after 1 year, and after 3 years from OHT. To evaluate the impact of the surgical technique, a control population treated with biatrial anastomosis was used. RESULTS: The most common IVCD was right bundle branch block (RBBB). Its presence at day 1 correlated with transpulmonary gradient before OHT. Its presence after 1 year and its development correlated with a 1-month acute rejection score≥2 (p = .050 and p = .006). The incidence of RBBB was higher in the biatrial control population (40.7% vs 23.8%, p < .001). CONCLUSIONS: RBBB is the most common IVCD. Its presence can be explained by a susceptibility of the right branch to heart positioning, pressure overload, and acute rejection. IVCDs do not affect prognosis.
Authors: A Osa; L Almenar; M A Arnau; L Martínez-Dolz; J Rueda; P Morillas; M Palencia Journal: J Heart Lung Transplant Date: 2000-02 Impact factor: 10.247
Authors: Mandeep R Mehra; Maria G Crespo-Leiro; Anne Dipchand; Stephan M Ensminger; Nicola E Hiemann; Jon A Kobashigawa; Joren Madsen; Jayan Parameshwar; Randall C Starling; Patricia A Uber Journal: J Heart Lung Transplant Date: 2010-07 Impact factor: 10.247
Authors: Daniel J Cantillon; Eiran Z Gorodeski; Marco Caccamo; Nicholas G Smedira; Bruce L Wilkoff; Randall C Starling; Walid Saliba Journal: J Heart Lung Transplant Date: 2009-08 Impact factor: 10.247
Authors: D Golshayan; C Seydoux; D G Berguer; F Stumpe; M Hurni; P Ruchat; A Fischer; X Mueller; H Sadeghi; L von Segesser; J J Goy Journal: Clin Cardiol Date: 1998-09 Impact factor: 2.882