Literature DB >> 27608958

Modelling ADHD: A review of ADHD theories through their predictions for computational models of decision-making and reinforcement learning.

Sigurd Ziegler1, Mads L Pedersen2, Athanasia M Mowinckel3, Guido Biele4.   

Abstract

Attention deficit hyperactivity disorder (ADHD) is characterized by altered decision-making (DM) and reinforcement learning (RL), for which competing theories propose alternative explanations. Computational modelling contributes to understanding DM and RL by integrating behavioural and neurobiological findings, and could elucidate pathogenic mechanisms behind ADHD. This review of neurobiological theories of ADHD describes predictions for the effect of ADHD on DM and RL as described by the drift-diffusion model of DM (DDM) and a basic RL model. Empirical studies employing these models are also reviewed. While theories often agree on how ADHD should be reflected in model parameters, each theory implies a unique combination of predictions. Empirical studies agree with the theories' assumptions of a lowered DDM drift rate in ADHD, while findings are less conclusive for boundary separation. The few studies employing RL models support a lower choice sensitivity in ADHD, but not an altered learning rate. The discussion outlines research areas for further theoretical refinement in the ADHD field. Copyright Â
© 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Attention deficit hyperactivity disorder; Computational model; Computational psychiatry; Decision-making; Dopamine; Dopamine transfer deficit theory; Drift-diffusion model; Dynamic developmental theory; Moderate brain arousal model; Neurobiology; Noradrenaline; Pathogenesis; Prediction error; Reinforcement learning

Mesh:

Year:  2016        PMID: 27608958     DOI: 10.1016/j.neubiorev.2016.09.002

Source DB:  PubMed          Journal:  Neurosci Biobehav Rev        ISSN: 0149-7634            Impact factor:   8.989


  30 in total

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4.  The drift diffusion model as the choice rule in reinforcement learning.

Authors:  Mads Lund Pedersen; Michael J Frank; Guido Biele
Journal:  Psychon Bull Rev       Date:  2017-08

5.  A New Spin on Spatial Cognition in ADHD: A Diffusion Model Decomposition of Mental Rotation.

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8.  ADHD symptoms map onto noise-driven structure-function decoupling between hub and peripheral brain regions.

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9.  Attention-deficit/hyperactivity disorder and the explore/exploit trade-off.

Authors:  Merideth A Addicott; John M Pearson; Julia C Schechter; Jeffrey J Sapyta; Margaret D Weiss; Scott H Kollins
Journal:  Neuropsychopharmacology       Date:  2020-10-11       Impact factor: 7.853

10.  Computational Modeling of Attentional Impairments in Disruptive Mood Dysregulation and Attention-Deficit/Hyperactivity Disorder.

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Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2020-11-24       Impact factor: 8.829

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