Chen Zhang1, Han-Zhu Qian1,2, Lu Yin1, Yu Liu1, Shiela M Strauss3, Yuhua Ruan4, Yiming Shao4, Hongyan Lu5, Sten H Vermund1,6. 1. a Vanderbilt Institute for Global Health , Vanderbilt University School of Medicine , Nashville , Tennessee , USA. 2. b Division of Epidemiology , Vanderbilt University School of Medicine , Nashville , Tennessee , USA. 3. c College of Nursing , New York University , New York , New York , USA. 4. d State Key Laboratory of Infectious Disease Prevention and Control (SKLID) , Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases , Beijing , China. 5. e Beijing Center for Disease Control and Prevention , Beijing , China. 6. f Department of Pediatrics , Vanderbilt University School of Medicine , Nashville , Tennessee , USA.
Abstract
BACKGROUND: High-risk sexual behaviors drive the HIV epidemic among men who have sex with men (MSM). Alcohol consumption and use of club drugs may increase sexual risk behaviors. We evaluated effects of drug and alcohol use on sexual behaviors with both their male and female partners as well as on HIV and syphilis infections among MSM in China. METHODS: As the part of a community randomized clinical trial that conducted among MSMin Beijing from 2013 to 2015, we recruited a total of 3,680 participants cross-sectionally. A self-administered questionnaire was employed to collect information regarding demographics, sexual behaviors, and a history of alcohol and drug use. Blood sample was collected for HIV and syphilis testing. RESULTS:A total of 3,588 MSM completed the survey and were included in the data analysis. The mean age was 29.9 with 97.3% of Han-ethnicity and 85.0% unmarried. The HIV and syphilis prevalence was 12.7% and 7.4%, respectively. Drug use was significantly associated with higher odds of HIV infection (aOR = 1.3, 95% Confidence Interval [CI] = 1.0,1.6), but not associated with syphilis. A higher level of alcohol consumption was similarly associated with higher odds of HIV risks with both male (e.g., condomless sex acts) and female partners (e.g., numbers of sexual partners). CONCLUSION: The association between drug and alcohol use and high-risk behaviors is notable among MSM in China. Integrated HIV interventions that target substance use among MSM may be more effective than programs that only target HIV alone.
RCT Entities:
BACKGROUND: High-risk sexual behaviors drive the HIV epidemic among men who have sex with men (MSM). Alcohol consumption and use of club drugs may increase sexual risk behaviors. We evaluated effects of drug and alcohol use on sexual behaviors with both their male and female partners as well as on HIV and syphilis infections among MSM in China. METHODS: As the part of a community randomized clinical trial that conducted among MSM in Beijing from 2013 to 2015, we recruited a total of 3,680 participants cross-sectionally. A self-administered questionnaire was employed to collect information regarding demographics, sexual behaviors, and a history of alcohol and drug use. Blood sample was collected for HIV and syphilis testing. RESULTS: A total of 3,588 MSM completed the survey and were included in the data analysis. The mean age was 29.9 with 97.3% of Han-ethnicity and 85.0% unmarried. The HIV and syphilis prevalence was 12.7% and 7.4%, respectively. Drug use was significantly associated with higher odds of HIV infection (aOR = 1.3, 95% Confidence Interval [CI] = 1.0,1.6), but not associated with syphilis. A higher level of alcohol consumption was similarly associated with higher odds of HIV risks with both male (e.g., condomless sex acts) and female partners (e.g., numbers of sexual partners). CONCLUSION: The association between drug and alcohol use and high-risk behaviors is notable among MSM in China. Integrated HIV interventions that target substance use among MSM may be more effective than programs that only target HIV alone.
Entities:
Keywords:
Alcohol use; China; HIV; drug use; sexual behavior; men who have sex with men
Authors: Jiang Du; Christina Lombardi; Elizabeth Evans; Haifeng Jiang; Min Zhao; Ying-Ying Meng Journal: Int J Infect Dis Date: 2012-04-24 Impact factor: 3.623
Authors: Albert Liu; David V Glidden; Peter L Anderson; K Rivet Amico; Vanessa McMahan; Megha Mehrotra; Javier R Lama; John MacRae; Juan Carlos Hinojosa; Orlando Montoya; Valdilea G Veloso; Mauro Schechter; Esper G Kallas; Suwat Chariyalerstak; Linda-Gail Bekker; Kenneth Mayer; Susan Buchbinder; Robert Grant Journal: J Acquir Immune Defic Syndr Date: 2014-12-15 Impact factor: 3.731
Authors: Tyler B Wray; Benjamin Grin; Leah Dorfman; Tiffany R Glynn; Christopher W Kahler; Brandon D L Marshall; Jacob J van den Berg; Nickolas D Zaller; Kendall J Bryant; Don Operario Journal: Drug Alcohol Rev Date: 2015-04-13
Authors: Lora L Sabin; Mary Bachman Desilva; Davidson H Hamer; Xu Keyi; Yuan Yue; Fan Wen; Li Tao; Harald K Heggenhougen; Lewis Seton; Ira B Wilson; Christopher J Gill Journal: AIDS Care Date: 2008-11
Authors: Shantrel S Canidate; Eric W Schrimshaw; Nancy Schaefer; Nioud Mulugeta Gebru; Noelani Powers; Stephen Maisto; Christina Parisi; Robert F Leeman; Sheldon Fields; Robert L Cook Journal: AIDS Behav Date: 2021-11-06