Literature DB >> 27607318

Infantile hemangiomas, complications and treatments.

Carol Erin Cheng1, Sheila Fallon Friedlander2,3,4.   

Abstract

Infantile hemangiomas (IHs) are the most common vascular tumors of infancy. While the majority regress without the need for intervention, approximately 10%, often site dependent, can cause serious complications and require treatment. IH complications can be categorized as life threatening, obstructive, ulcerative or disfiguring. Life threatening complications include airway and hepatic IHs. Functional complications obstructing vital structures or impairing function include periocular, nasal, labial, parotid, auricular, and breast IHs. Local complications arise from ulceration or those in cosmetically sensitive areas. Therapeutic options for complicated IHs include pharmacologic (topical or systemic), surgical, or laser interventions. Topical agents are best employed for small, superficial, and localized IHs; while systemic therapy is reserved for larger IHs and those with more aggressive growth characteristics with propranolol as first-line therapy. ©2016 Frontline Medical Communications.

Entities:  

Keywords:  airway IH; auricular IH; breast IH; infantile hemangiomas; lip IH; multiple cutaneous hemangiomas; nasal IH; parotid IH; periocular IH; propranolol; timolol; ulcerated IH

Mesh:

Substances:

Year:  2016        PMID: 27607318     DOI: 10.12788/j.sder.2016.050

Source DB:  PubMed          Journal:  Semin Cutan Med Surg        ISSN: 1085-5629


  13 in total

1.  Kasabach-Merritt syndrome combined with hypercalcemia: A case report.

Authors:  Runying Zou; Fang Peng; Tian Yu; Saizhen Zeng; Yalan You; Keke Chen; Hui Zou; Xin Tian; Chengguang Zhu; Xiangling He
Journal:  Exp Ther Med       Date:  2017-10-18       Impact factor: 2.447

2.  Outcomes of surgical treatment for hemangiomas.

Authors:  Jeffrey Cheng; Beiyu Liu; Hui-Jie Lee
Journal:  Pediatr Dermatol       Date:  2019-02-22       Impact factor: 1.588

3.  Timing and Efficacy of 595-nm Pulsed-Dye Laser Combined with 0.5% Timolol Maleate Solution in the Treatment of Superficial Infantile Hemangiomas.

Authors:  Weikang Shi; Huiyi He; Jicong Jiang; Yu Gao; Hehe Quan
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-11-02

Review 4.  Update on Treatment of Infantile Hemangiomas: What's New in the Last Five Years?

Authors:  Laura Macca; Domenica Altavilla; Luca Di Bartolomeo; Natasha Irrera; Francesco Borgia; Federica Li Pomi; Federico Vaccaro; Violetta Squadrito; Francesco Squadrito; Mario Vaccaro
Journal:  Front Pharmacol       Date:  2022-05-26       Impact factor: 5.988

5.  Morphological, genetic and clinical correlations in infantile hemangiomas and their mimics.

Authors:  Alina Costina Luca; Ingrith Crenguţa Miron; Laura Mihaela Trandafir; Elena Cojocaru; Ioana Alexandra Pădureţ; Mioara Florentina Trandafirescu; Alin Constantin Iordache; Elena Ţarcă
Journal:  Rom J Morphol Embryol       Date:  2020 Jul-Sep       Impact factor: 1.033

6.  Identification of novel potential biomarkers in infantile hemangioma via weighted gene co-expression network analysis.

Authors:  Bin Xie; Xiongming Zhou; Jiaxuan Qiu
Journal:  BMC Pediatr       Date:  2022-05-01       Impact factor: 2.567

Review 7.  Interdisciplinary Management of Head and Neck Vascular Anomalies: Clinical Presentation, Diagnostic Findings and Minimalinvasive Therapies.

Authors:  Maliha Sadick; Walter A Wohlgemuth; Roland Huelse; Bettina Lange; Thomas Henzler; Stefan O Schoenberg; Haneen Sadick
Journal:  Eur J Radiol Open       Date:  2017-05-14

8.  Effects of Propranolol on Neurodevelopmental Outcomes in Patients with Infantile Hemangioma: A Case-Control Study.

Authors:  Chuan Wang; Qi Wang; Bo Xiang; Siyuan Chen; Fei Xiong; Yi Ji
Journal:  Biomed Res Int       Date:  2018-02-25       Impact factor: 3.411

9.  Continuous delivery of propranolol from liposomes-in-microspheres significantly inhibits infantile hemangioma growth.

Authors:  Xiaonan Guo; Xiaoshuang Zhu; Dakan Liu; Yubin Gong; Jing Sun; Changxian Dong
Journal:  Int J Nanomedicine       Date:  2017-09-18

10.  Over-expression of PPAR-γ2 gene enhances the adipogenic differentiation of hemangioma-derived mesenchymal stem cells in vitro and in vivo.

Authors:  Si-Ming Yuan; Yao Guo; Qian Wang; Yuan Xu; Min Wang; Hai-Ni Chen; Wei-Min Shen
Journal:  Oncotarget       Date:  2017-12-26
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