Francesca Donato1, Giacomo Garzaro1, Enrico Pira1, Paolo Boffetta2. 1. Department of Public Health Sciences and Pediatrics, Turin University, Turin, Italy. 2. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA. paolo.boffetta@mssm.edu.
Abstract
OBJECTIVES: To analyze overall and cause-specific mortality, especially from cancer, among cement production workers. INTRODUCTION: Results from some epidemiological studies suggested an increased risk of overall mortality and of stomach cancer associated with employment in the cement production, but the presence of a hazard and, if present, the magnitude of a risk have not been precisely quantified. We conducted a systematic review and meta-analysis of data on mortality from all causes, cardiovascular or respiratory diseases, and cancer among cement workers. METHODS: The literature search in PubMed and Scopus up to February 2016 and with appropriate keywords on mortality among cement workers revealed 188 articles which were screened. A total of 117 articles were reviewed in full text and 12 articles, referring to 11 study populations, were found to be relevant and of sufficient quality for further analysis. Meta-analyses were performed using a random-effects model. RESULTS: Eight cohort studies, one proportionate mortality study, and two case-control studies were identified. The summary RRs were 0.89 [95 % confidence interval (CI) 0.76-1.01] for all-cause mortality, 0.94 (95 %, CI 0.80-1.08) for cancer mortality, 1.07 (95 % CI 0.79-1.35) for lung cancer mortality, and 0.93 (95 % CI 0.70-1.17) for stomach cancer mortality, respectively. Significant heterogeneity in results was observed among studies. CONCLUSION: The present meta-analysis does not provide evidence of increased risk of overall mortality, as well as cancer, cardiovascular or respiratory mortality in relation to employment in cement production.
OBJECTIVES: To analyze overall and cause-specific mortality, especially from cancer, among cement production workers. INTRODUCTION: Results from some epidemiological studies suggested an increased risk of overall mortality and of stomach cancer associated with employment in the cement production, but the presence of a hazard and, if present, the magnitude of a risk have not been precisely quantified. We conducted a systematic review and meta-analysis of data on mortality from all causes, cardiovascular or respiratory diseases, and cancer among cement workers. METHODS: The literature search in PubMed and Scopus up to February 2016 and with appropriate keywords on mortality among cement workers revealed 188 articles which were screened. A total of 117 articles were reviewed in full text and 12 articles, referring to 11 study populations, were found to be relevant and of sufficient quality for further analysis. Meta-analyses were performed using a random-effects model. RESULTS: Eight cohort studies, one proportionate mortality study, and two case-control studies were identified. The summary RRs were 0.89 [95 % confidence interval (CI) 0.76-1.01] for all-cause mortality, 0.94 (95 %, CI 0.80-1.08) for cancer mortality, 1.07 (95 % CI 0.79-1.35) for lung cancer mortality, and 0.93 (95 % CI 0.70-1.17) for stomach cancer mortality, respectively. Significant heterogeneity in results was observed among studies. CONCLUSION: The present meta-analysis does not provide evidence of increased risk of overall mortality, as well as cancer, cardiovascular or respiratory mortality in relation to employment in cement production.
Authors: William Dab; Michel Rossignol; Danièle Luce; Jacques Bénichou; Alain Marconi; Philippe Clément; Michel Aubier; Denis Zmirou-Navier; Lucien Abenhaim Journal: Int Arch Occup Environ Health Date: 2010-04-01 Impact factor: 3.015
Authors: Sarah S Cohen; Margaret M Sadoff; Xiaohui Jiang; Jon P Fryzek; David H Garabrant Journal: Occup Environ Med Date: 2014-08-20 Impact factor: 4.402
Authors: Vincent James Cogliano; Robert Baan; Kurt Straif; Yann Grosse; Béatrice Lauby-Secretan; Fatiha El Ghissassi; Véronique Bouvard; Lamia Benbrahim-Tallaa; Neela Guha; Crystal Freeman; Laurent Galichet; Christopher P Wild Journal: J Natl Cancer Inst Date: 2011-12-12 Impact factor: 13.506
Authors: D F Stroup; J A Berlin; S C Morton; I Olkin; G D Williamson; D Rennie; D Moher; B J Becker; T A Sipe; S B Thacker Journal: JAMA Date: 2000-04-19 Impact factor: 56.272
Authors: Paolo Boffetta; Joseph K McLaughlin; Carlo La Vecchia; Robert E Tarone; Loren Lipworth; William J Blot Journal: J Natl Cancer Inst Date: 2008-07-08 Impact factor: 13.506
Authors: Aleksei Kholodov; Alexander Zakharenko; Vladimir Drozd; Valery Chernyshev; Konstantin Kirichenko; Ivan Seryodkin; Alexander Karabtsov; Svetlana Olesik; Ekaterina Khvost; Igor Vakhnyuk; Vladimir Chaika; Antonios Stratidakis; Marco Vinceti; Dimosthenis Sarigiannis; A Wallace Hayes; Aristidis Tsatsakis; Kirill Golokhvast Journal: Heliyon Date: 2020-02-24