Literature DB >> 20358379

Cancer mortality study among French cement production workers.

William Dab1, Michel Rossignol, Danièle Luce, Jacques Bénichou, Alain Marconi, Philippe Clément, Michel Aubier, Denis Zmirou-Navier, Lucien Abenhaim.   

Abstract

PURPOSE: To analyse the mortality and its causes, especially cancer, among French cement production workers.
METHODS: A cohort of all workers employed at least 1 year in one of the main four cement companies in France was assembled (9,118 workers, 122,124 person-years of follow-up between 1990 and 2005). A common job titles classification was used to analyse occupational risk factors. We conducted a standardized mortality ratio analysis based on age, gender and calendar-period-specific national mortality rates and explored the combined effect of job titles and duration through an internal Cox regression analysis.
RESULTS: The number of deaths during the follow-up period was 430 (4.7%). Malignant neoplasm was the cause of 48.1% of deaths. Overall, a deficit in all-causes mortality (standardized mortality ratio (SMR): 0.68, 95% confidence interval (CI) 0.61-0.74) and in cancer mortality (SMR: 0.80, CI 0.69-0.92) was observed. Working in the quarry, yard and shipping sectors was associated with a 50% higher all-causes mortality risk in comparison with the administrative sector.
CONCLUSIONS: This cohort study does not support previous observations that cement workers are at higher risk of cancer mortality than the general population. The length of follow-up should be increased, and specific exposures deserve analysis.

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Year:  2010        PMID: 20358379     DOI: 10.1007/s00420-010-0530-6

Source DB:  PubMed          Journal:  Int Arch Occup Environ Health        ISSN: 0340-0131            Impact factor:   3.015


  29 in total

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