Literature DB >> 27603723

Computational Study of Aqueous Humor Dynamics Assessing the Vault and the Pupil Diameter in Two Posterior-Chamber Phakic Lenses.

José Ignacio Fernández-Vigo1, Ana Macarro-Merino2, Joaquín Fernández-Francos3, Lucía De-Pablo-Gómez-de-Liaño2, José María Martínez-de-la-Casa4, Julián García-Feijóo4, José Ángel Fernández-Vigo5.   

Abstract

PURPOSE: To compare the behavior of aqueous humor (AH) and analyze flow differences by comparing the volume and velocity of the flow after two different models of implantable collamer lens (ICL) placement.
METHODS: Computational fluid dynamics with numerical simulation using Ansys Fluent software was performed to compare the AH flow through a peripheral iridotomy (PI), which is typically performed after implantation of a V4b lens to the central hole of a V4c lens. The volume and flow rate in 24 scenarios were compared according to the type of lens, pupil diameter (PD) (3.5 or 5.5 mm), the vault (100, 350, and 800 μm) and the PI (single or double, 180 or 360 μm).
RESULTS: With a standard vault (350 μm) and a PD of 3.5 mm, the volume of AH that flows from the posterior to the anterior chamber through the PI (V4b lens: 73.4% in 360 μm and 17.3% in 180 μm) and for the central hole (V4c lens: 75.7%) is larger than in the case of a PD of 5.5 mm (13.9%, 0.91%, and 15.3% respectively). When the vault is low (100; PD 3.5 mm), the volume of AH that reaches the central hole of the V4c lens is diminished (52.0%), being 5.1% if the pupil is enlarged.
CONCLUSIONS: AH flow varies depending on the type of ICL implanted, whether it is implanted with an iridotomy or a central hole on the lens, the PD, and the vault.

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Year:  2016        PMID: 27603723     DOI: 10.1167/iovs.16-19900

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  4 in total

1.  Computational simulation of aqueous humour dynamics in the presence of a posterior-chamber versus iris-fixed phakic intraocular lens.

Authors:  José Ignacio Fernández-Vigo; Alfonso C Marcos; Rafael Agujetas; José María Montanero; Inés Sánchez-Guillén; Julián García-Feijóo; Adrián Pandal-Blanco; José Ángel Fernández-Vigo; Ana Macarro-Merino
Journal:  PLoS One       Date:  2018-08-13       Impact factor: 3.240

2.  Evaluation of Disk Halo Size after Implantation of a Collamer Lens with a Central Hole (ICL V4c).

Authors:  Xun Chen; Tian Han; Feng Zhao; Huamao Miao; Xiaoying Wang; Xingtao Zhou
Journal:  J Ophthalmol       Date:  2019-08-14       Impact factor: 1.909

3.  Geometric Model and Numerical Study of Aqueous Humor Hydrodynamics in the Human Eye.

Authors:  Hao Tang; Zhangrong Qin; Binghai Wen
Journal:  Comput Math Methods Med       Date:  2022-04-11       Impact factor: 2.809

4.  Three-year follow-up of posterior chamber phakic intraocular lens with a central port design after deep anterior lamellar keratoplasty.

Authors:  Belén Alfonso-Bartolozzi; Carlos Lisa; Luis Fernández-Vega-Cueto; Begoña Baamonde; David Madrid-Costa; José F Alfonso
Journal:  Eye Vis (Lond)       Date:  2022-09-07
  4 in total

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