Lars Holm1,2, Stine Klejs Rahbek3, Jean Farup3, Mikkel Holm Vendelbo4,5, Kristian Vissing3. 1. Institute of Sports Medicine, Department of Orthopedic Surgery M, Bispebjerg Hospital, Copenhagen, Denmark. 2. Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. 3. Section for Sport Science, Department of Public Health, Aarhus University, Aarhus, Denmark. 4. Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, Denmark. 5. Department of Nuclear Medicine and PET Center, Aarhus University Hospital, Aarhus, Denmark.
Abstract
INTRODUCTION: In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions. METHODS:Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring-13 C6 -phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1-5, as well as 1-3 and 3-5 hours after contractions and nutrient intake. RESULTS: During the 1-3-hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P < 0.01), independent of supplementation type and, during the 3-5-hour recovery, WPH had a higher FSR than CHO (P < 0.05), independent of prior contraction mode. CONCLUSIONS: The later appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle contractions lends support to its ability to promote recovery of the muscle connective tissue matrix after exercise. Muscle Nerve 55: 128-130, 2017.
RCT Entities:
INTRODUCTION: In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions. METHODS: Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring-13 C6 -phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1-5, as well as 1-3 and 3-5 hours after contractions and nutrient intake. RESULTS: During the 1-3-hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P < 0.01), independent of supplementation type and, during the 3-5-hour recovery, WPH had a higher FSR than CHO (P < 0.05), independent of prior contraction mode. CONCLUSIONS: The later appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle contractions lends support to its ability to promote recovery of the muscle connective tissue matrix after exercise. Muscle Nerve 55: 128-130, 2017.
Authors: Matthias Gumpenberger; Barbara Wessner; Alexandra Graf; Marco V Narici; Christian Fink; Sepp Braun; Christian Hoser; Anthony J Blazevich; Robert Csapo Journal: Int J Mol Sci Date: 2020-09-25 Impact factor: 5.923
Authors: Jorn Trommelen; Andrew M Holwerda; Joan M Senden; Joy P B Goessens; Janneau VAN Kranenburg; Annemie P Gijsen; Lex B Verdijk; Luc J C VAN Loon Journal: Med Sci Sports Exerc Date: 2020-09