Jennifer Smith1, Christine Poon2, Nicole Gilroy3, Masura Kabir4, Lisa Brice5, Gemma Dyer3,6, Megan Hogg7, Matthew Greenwood5,6,8, John Moore9, Mark Hertzberg10, Louisa Brown11, Jeff Tan9, Gillian Huang7, John Kwan7, Stephen Larsen12, Christopher Ward5,6,8, Ian Kerridge5,6,8. 1. Nutrition Services, Royal North Shore Hospital, Building 30, Level 2, Pacific Highway, St Leonards, NSW, 2065, Australia. Jennifer.Smith4@health.nsw.gov.au. 2. Nutrition Services, Royal North Shore Hospital, Building 30, Level 2, Pacific Highway, St Leonards, NSW, 2065, Australia. 3. Blood and Marrow Transplant Network, New South Wales Agency for Clinical Innovation, Sydney, NSW, Australia. 4. Westmead Breast Cancer Institute, Sydney, NSW, Australia. 5. Department of Haematology, Royal North Shore Hospital, Sydney, NSW, Australia. 6. Northern Clinical School, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia. 7. Department of Haematology, Westmead Hospital, Sydney, NSW, Australia. 8. Northern Blood Research Centre, Kolling Institute, University of Sydney, Sydney, NSW, Australia. 9. Department of Haematology, St Vincent's Hospital, Sydney, NSW, Australia. 10. Department of Haematology, Prince of Wales Hospital, Sydney, NSW, Australia. 11. Department of Haematology, Calvary Mater Newcastle, Sydney, NSW, Australia. 12. Institute of Haematology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Abstract
PURPOSE: The aims of this study were to describe the long-term nutrition, body weight and body image issues facing survivors of Allogeneic Blood and Marrow Transplant (BMT) and their impact on quality of life. It also describes survivors' perception of enteral feeding during BMT. METHODS: Four hundred and forty-one survivors who had undergone a BMT in NSW, Australia between 2000 and 2012 (n = 441/583) completed the Sydney Post BMT Study Survey (SPBS). RESULTS: Forty-five percent of survivors less than 2-year post-transplant reported a dry mouth, 36 % reported mouth ulcers and 19 % had diarrhoea. This was consistent across all survivor groups, regardless of time since transplant. Patients with one or more gastrointestinal (GI) symptoms had significantly lower quality of life scores. There was a significant difference in quality of life scores when comparing those with no GI symptoms to those with one or more symptoms (P = <0.0001). Quality of life was significantly higher in those who once again enjoyed mealtimes (P < 0.0001). Males were more likely to be satisfied with their body weight compared to females (P = 0.009). The median body mass index (BMI) for all patients reporting body weight satisfaction was significantly lower (BMI 23.5) than those reporting dissatisfaction (BMI 27.5) (P = <0.0001). Survivors who had a normal BMI had significantly higher rates of body weight satisfaction compared to underweight, overweight and obese survivors (P = <0.0001). Those survivors who were overweight or obese were significantly more likely to be diabetic (P = 0.008). CONCLUSION: This study revealed an important relationship between gastrointestinal symptoms, body weight and body image and survivor's quality of life. It provides further support for the importance of nutrition therapy post-BMT.
PURPOSE: The aims of this study were to describe the long-term nutrition, body weight and body image issues facing survivors of Allogeneic Blood and Marrow Transplant (BMT) and their impact on quality of life. It also describes survivors' perception of enteral feeding during BMT. METHODS: Four hundred and forty-one survivors who had undergone a BMT in NSW, Australia between 2000 and 2012 (n = 441/583) completed the Sydney Post BMT Study Survey (SPBS). RESULTS: Forty-five percent of survivors less than 2-year post-transplant reported a dry mouth, 36 % reported mouth ulcers and 19 % had diarrhoea. This was consistent across all survivor groups, regardless of time since transplant. Patients with one or more gastrointestinal (GI) symptoms had significantly lower quality of life scores. There was a significant difference in quality of life scores when comparing those with no GI symptoms to those with one or more symptoms (P = <0.0001). Quality of life was significantly higher in those who once again enjoyed mealtimes (P < 0.0001). Males were more likely to be satisfied with their body weight compared to females (P = 0.009). The median body mass index (BMI) for all patients reporting body weight satisfaction was significantly lower (BMI 23.5) than those reporting dissatisfaction (BMI 27.5) (P = <0.0001). Survivors who had a normal BMI had significantly higher rates of body weight satisfaction compared to underweight, overweight and obese survivors (P = <0.0001). Those survivors who were overweight or obese were significantly more likely to be diabetic (P = 0.008). CONCLUSION: This study revealed an important relationship between gastrointestinal symptoms, body weight and body image and survivor's quality of life. It provides further support for the importance of nutrition therapy post-BMT.
Entities:
Keywords:
BMI; Blood and marrow transplantation- BMT; Cancer survivorship; Late complications; Nutrition; Quality of life
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