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Literature DB >> 27581767

Dual-Stage Crosslinking of a Gel-Phase Bioink Improves Cell Viability and Homogeneity for 3D Bioprinting.

Karen Dubbin¹, Yuki Hori¹, Kazuomori K Lewis², Sarah C Heilshorn³.

Abstract

Current bioinks for cell-based 3D bioprinting are not suitable for technology scale-up due to the challenges of cell sedimentation, cell membrane damage, and cell dehydration. A novel bioink hydrogel is presented with dual-stage crosslinking specifically designed to overcome these three major hurdles. This bioink enables the direct patterning of highly viable, multicell type constructs with long-term spatial fidelity.

Keywords: bioink; biomaterials; bioprinting; hydrogels; tissue engineering

Mesh：

Substances：

Year: 2016 PMID： 27581767 DOI： 10.1002/adhm.201600636

Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933

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Cited

22 in total

1. Polymeric 3D Printed Structures for Soft-Tissue Engineering.

Authors: Scott Stratton; Ohan S Manoukian; Ravi Patel; Adam Wentworth; Swetha Rudraiah; Sangamesh G Kumbar
Journal: J Appl Polym Sci Date: 2017-09-14 Impact factor: 3.125

2. Bioprinting 101: Design, Fabrication, and Evaluation of Cell-Laden 3D Bioprinted Scaffolds.

Authors: Kaivalya A Deo; Kanwar Abhay Singh; Charles W Peak; Daniel L Alge; Akhilesh K Gaharwar
Journal: Tissue Eng Part A Date: 2020-03 Impact factor: 3.845

3. Quantitative criteria to benchmark new and existing bio-inks for cell compatibility.

Authors: Karen Dubbin; Anthony Tabet; Sarah C Heilshorn
Journal: Biofabrication Date: 2017-09-01 Impact factor: 9.954

4. Bioprinting of stem cell expansion lattices.

Authors: Christopher D Lindsay; Julien G Roth; Bauer L LeSavage; Sarah C Heilshorn
Journal: Acta Biomater Date: 2019-05-13 Impact factor: 8.947

Review 5. 3D Bioprinting of Cell-Laden Hydrogels for Improved Biological Functionality.

Authors: Sarah M Hull; Lucia G Brunel; Sarah C Heilshorn
Journal: Adv Mater Date: 2021-10-20 Impact factor: 30.849

6. Stereolithographic printing of ionically-crosslinked alginate hydrogels for degradable biomaterials and microfluidics.

Authors: Thomas M Valentin; Susan E Leggett; Po-Yen Chen; Jaskiranjeet K Sodhi; Lauren H Stephens; Hayley D McClintock; Jea Yun Sim; Ian Y Wong
Journal: Lab Chip Date: 2017-10-11 Impact factor: 6.799

Dual-Stage Crosslinking of a Gel-Phase Bioink Improves Cell Viability and Homogeneity for 3D Bioprinting.

1. Polymeric 3D Printed Structures for Soft-Tissue Engineering.

2. Bioprinting 101: Design, Fabrication, and Evaluation of Cell-Laden 3D Bioprinted Scaffolds.

3. Quantitative criteria to benchmark new and existing bio-inks for cell compatibility.

4. Bioprinting of stem cell expansion lattices.

Review 5. 3D Bioprinting of Cell-Laden Hydrogels for Improved Biological Functionality.

6. Stereolithographic printing of ionically-crosslinked alginate hydrogels for degradable biomaterials and microfluidics.

Review 7. From Shape to Function: The Next Step in Bioprinting.

Review 8. Emulating Human Tissues and Organs: A Bioprinting Perspective Toward Personalized Medicine.

9. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks.

Review 10. Crosslinking Strategies for 3D Bioprinting of Polymeric Hydrogels.